Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Ascorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | TST | Q16762 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.36 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ascorbic Acid SCHEMBL27745901 | 1.00 | MAPT (0.71) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL31356975 | 1.00 | MAPT (0.71) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Phthalic Acid SCHEMBL30259716 | 0.89 | MAPT (0.71) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Benzoyl Peroxide SCHEMBL27419791 | 0.88 | LMNA (0.66) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL9357004 | 0.88 | MAPT (0.66) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL5033864 | 0.87 | MAPT (0.78) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL29992966 | 0.86 | MAPT (0.89) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL4146647 | 0.86 | MAPT (0.96) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL22589022 | 0.86 | MAPT (0.96) | MAPTL3MBTL1LMNATYRHSPD1 | |
| Ascorbic Acid SCHEMBL30461160 | 0.86 | MAPT (0.96) | MAPTL3MBTL1LMNATYRHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312987-C | Method of preventing and treating red fat large small moth by large scale artificial breeding, releasing large gnawing wax shell | YANG ZHONGQI (CN) | 2007-05-02 | — | — | CN | claimed |
| CN-1312987-C | Method of preventing and treating red fat large small moth by large scale artificial breeding, releasing large gnawing wax shell | YANG ZHONGQI (CN) | 2007-05-02 | — | — | CN | disclosed |
| US-20060148021-A1 | Extraction of a proteinaceous macromolecule from a biological sample | PROTEOME SYSTEM INTELLECTUAL PROPERTY PTY LTD | 2006-07-06 | — | — | US | disclosed |
| WO-2004041848-A1 | IMPROVED EXTRACTION OF A PROTEINACEOUS MACROMOLECULE FROM A BIOLOGICAL SAMPLE | PROTEOME SYSTEMS INTELLECTUAL PROPERTY PTY LTD (AU) | 2004-05-21 | — | — | WO | disclosed |
| US-6663904-B2 | Shelf-stable soft pretzel | RECOT, INC. | 2003-12-16 | — | — | US | disclosed |
| US-6444244-B1 | Method for making a shelf-stable soft pretzel | RECOT, INC. | 2002-09-03 | — | — | US | disclosed |
| US-20020041918-A1 | Shelf-stable soft pretzel | FRITO-LAY AMERICA, INC. | 2002-04-11 | — | — | US | disclosed |
| US-4981782-A | Synthetic peptides for diagnosis and prevention of influenza virus infection and their use | SRI INTERNATIONAL (US) | 1991-01-01 | — | — | US | disclosed |