Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Ascorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | TST | Q16762 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.34 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ascorbic Acid SCHEMBL27745901 | 0.88 | MAPT (0.71) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL31356975 | 0.88 | MAPT (0.71) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL5914554 | 0.88 | MAPT (0.71) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL21372602 | 0.87 | LMNA (0.81) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL10535642 | 0.85 | MAPT (0.76) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL21372605 | 0.84 | MAPT (0.81) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL21372601 | 0.84 | MAPT (0.81) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Benzoyl Peroxide SCHEMBL27419791 | 0.84 | LMNA (0.66) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL165191 | 0.83 | MAPT (0.78) | MAPTLMNAL3MBTL1TYRHSPD1 | |
| Ascorbic Acid SCHEMBL5033864 | 0.83 | MAPT (0.78) | MAPTLMNAL3MBTL1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622992-A1 | STORAGE STABLE CALCIUM-SUPPLEMENTED BEVERAGE CONCENTRATES | THE PROCTER & GAMBLE COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993012672-A1 | STORAGE STABLE CALCIUM-SUPPLEMENTED BEVERAGE CONCENTRATES | THE PROCTER & GAMBLE COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |