SCHEMBL5916616

SCHEMBL5916616

CCCCC(N(C)C(=O)O)[SiH](OC)OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.37
CA1 P00915 2/20 0.37
MAPK1 P28482 1/20 0.36
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
GPR84 Q9NQS5 5/20 0.32
FFAR1 O14842 1/20 0.32
MAPT P10636 1/20 0.31
LCK P06239 1/20 0.31
PPARD Q03181 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ACHE P22303 1/20 0.30
BACE1 P56817 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916744 0.93 GPR84 (0.41) CA2ZDHHC7GPR84FFAR1MAPT
SCHEMBL5916785 0.93 GPR84 (0.41) CA2ZDHHC7GPR84FFAR1MAPT
SCHEMBL5916625 0.89 CHRM1 (0.34) TDP1
SCHEMBL5916722 0.85 CA2 (0.35) CA2CA1MAPK1SLC1A3SLC1A2
SCHEMBL5916522 0.82
SCHEMBL5916697 0.81 CA2 (0.36) CA2CA1MAPK1SLC1A3SLC1A2
SCHEMBL5916732 0.80 GPR84 (0.37) CA1SLC1A2SLC1A1ZDHHC7GPR84
SCHEMBL5916743 0.79 GPR84 (0.40) CA2ZDHHC7GPR84FFAR1MAPT
SCHEMBL5916606 0.79 GPR84 (0.40) CA2ZDHHC7GPR84FFAR1MAPT
SCHEMBL5916589 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
EP-1328586-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-23 EP disclosed
WO-2002034838-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-02 WO disclosed