SCHEMBL5916645

SCHEMBL5916645

CCO[Si](CC)(CCCN(CC)C(=O)O)OCC

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
ALDH1A1 P00352 1/20 0.30
CA2 P00918 1/20 0.30
NPC1 O15118 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916678 0.95 LMNA (0.33) LMNACA12CA1CA9
SCHEMBL5916597 0.94 LMNA (0.32) LMNACA12CA1CA9
SCHEMBL5916702 0.85 CA12 (0.34) LMNACA12CA1CA9CA2
SCHEMBL443029 0.83 LMNA (0.36) LMNACA12CA1CA9ALDH1A1
SCHEMBL5916730 0.81 BCHE (0.30)
SCHEMBL5916624 0.81 LMNA (0.35) LMNACA12CA1CA9ALDH1A1
SCHEMBL5916717 0.80 CA12 (0.33) LMNACA12CA1CA9CA2
SCHEMBL5916559 0.79 CA12 (0.33) CA12CA1CA9
SCHEMBL5916677 0.79 CA12 (0.33) CA12CA1CA9
SCHEMBL5916941 0.78 LMNA (0.35) LMNACA12CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed