SCHEMBL5916624

SCHEMBL5916624

CCO[Si](C)(CCCN(CC)C(=O)O)OCC

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 1/20 0.31
NPC1 O15118 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RAB9A P51151 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916811 0.95 LMNA (0.34) LMNACA12CA1CA9ALDH1A1
SCHEMBL7572215 0.93 LMNA (0.33) LMNACA12CA1CA9
SCHEMBL5916600 0.93 LMNA (0.33) LMNACA12CA1CA9
SCHEMBL5916506 0.89 LMNA (0.33) LMNAALDH1A1
SCHEMBL443029 0.84 LMNA (0.36) LMNACA12CA1CA9ALDH1A1
SCHEMBL3038689 0.84 CA12 (0.31) LMNACA12CA1CA9
SCHEMBL19970654 0.82 CA12 (0.31) CA12CA1CA9
SCHEMBL5916645 0.81 LMNA (0.34) LMNACA12CA1CA9ALDH1A1
SCHEMBL5916705 0.81 BCHE (0.31)
SCHEMBL961553 0.81 ALOX15 (0.30) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130079449-A1 Polymer Composition and Method SOLVAY SA (BE) 2013-03-28 US claimed
WO-2013043321-A1 POLYMER COMPOSITION AND METHOD CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-03-28 WO claimed
US-20130079449-A1 Polymer Composition and Method SOLVAY SA (BE) 2013-03-28 US disclosed
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
EP-0409411-A2 Magnetic recording medium with cured surface coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-23 EP disclosed
US-4529659-A Magnetic recording member and process for manufacturing the same NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1985-07-16 US disclosed