SCHEMBL592174

SCHEMBL592174

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)c1ccc(C=Cc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.55
KCNH2 Q12809 1/20 0.51
PTGS2 P35354 5/20 0.50
MEN1 O00255 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
APP P05067 1/20 0.45
FBP1 P09467 1/20 0.44
INSR P06213 1/20 0.44
PTGS1 P23219 2/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL592173 1.00 MAPT (0.55) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9358488 1.00 MAPT (0.55) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9358492 1.00 MAPT (0.55) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9362316 0.99 MAPT (0.56) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9362320 0.99 MAPT (0.56) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9847215 0.97 MAPT (0.52) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9847350 0.96 MAPT (0.54) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL6474787 0.94 MAPT (0.61) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9358403 0.94 MAPT (0.61) MAPTKCNH2PTGS2MEN1ALDH1A1
SCHEMBL9847256 0.93 MAPT (0.54) MAPTKCNH2PTGS2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11150358-B2 Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry RIKEN (JP) 2021-10-19 US disclosed
US-20200333474-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY RIKEN (JP) 2020-10-22 US disclosed
EP-3686632-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY Riken (JP) 2020-07-29 EP disclosed
US-20170023681-A1 PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER NEW YORK UNIVERSITY 2017-01-26 US disclosed
US-9086489-B2 Personal and area self-indicating instant radiation alert dosimeter JP LABORATORIES, INC (US) 2015-07-21 US disclosed
US-8872134-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC (US) 2014-10-28 US disclosed
US-20120205591-A1 SELF INDICATING RADIATION ALERT DOSIMETER PATEL GORDHABHAI N (US) 2012-08-16 US disclosed
US-20120181453-A1 PERSONAL AND AREA SELF-INDICATING INSTANT RADIATION ALERT DOSIMETER JP LABORATORIES INC. 2012-07-19 US disclosed
US-8115182-B1 Personal and area self-indicating radiation alert dosimeter JP LABORATORIES INC. 2012-02-14 US disclosed
US-7476874-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC. (US) 2009-01-13 US disclosed
US-7227158-B1 Stick-on self-indicating instant radiation dosimeter JP LABS, INC. (US) 2007-06-05 US disclosed
US-20060145091-A1 Self indicating radiation alert dosimeter JP LABORATORIES INC. 2006-07-06 US disclosed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 EP disclosed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 WO disclosed