Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592174 | 1.00 | MAPT (0.55) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL592173 | 1.00 | MAPT (0.55) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9358492 | 1.00 | MAPT (0.55) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9362316 | 0.99 | MAPT (0.56) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9362320 | 0.99 | MAPT (0.56) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9847215 | 0.97 | MAPT (0.52) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9847350 | 0.96 | MAPT (0.54) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL6474787 | 0.94 | MAPT (0.61) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9358403 | 0.94 | MAPT (0.61) | MAPTKCNH2PTGS2MEN1ALDH1A1 | |
| SCHEMBL9847256 | 0.93 | MAPT (0.54) | MAPTKCNH2PTGS2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418654-B1 | Coupler-type optical switch and process for producing the same | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5108200-A | Medium surrounding photocoupler contains optic material who refrative index changes by action of electric or magnetic field | SUMITOMO ELECTRIC INDUSTRIES LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| EP-0418654-A1 | Coupler-type optical switch and process for producing the same | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |
| EP-0374227-A1 | GUEST/HOST POLYMERS FOR NONLINEAR OPTICS | MERCK PATENT GmbH (DE) | 1990-06-27 | — | — | EP | disclosed |
| WO-1989012247-A1 | GUEST/HOST POLYMERS FOR NONLINEAR OPTICS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-12-14 | — | — | WO | disclosed |