Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5555814 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL8187512 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL8716653 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL1591363 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL1615802 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL4097452 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL28301301 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL1591297 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL694363 | 0.96 | — | — | |
| Acetic Acid SCHEMBL7025787 | 0.93 | FFAR3 (0.50) | FFAR3LCKFYNLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1932 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110967441-B | Rapid thin-layer identification method for Jinshi Liyan granules | 河北中医学院 | 2021-07-02 | — | — | CN | claimed |
| WO-2021128807-A1 | RAPID THIN-LAYER IDENTIFICATION METHOD OF RADIX PUERARIAE INTESTINE-CLEARING GRANULES | 河北中医学院 | 2021-07-01 | — | — | WO | claimed |
| CN-110988248-B | Rapid thin-layer identification method for radix puerariae intestine clearing granules | 河北中医学院 | 2021-06-18 | — | — | CN | claimed |
| CN-110988248-A | Rapid thin-layer identification method for radix puerariae intestine clearing granules | 河北中医学院 | 2020-04-10 | — | — | CN | claimed |
| CN-110967441-A | Rapid thin-layer identification method for Jinshi Liyan granules | 河北中医学院 | 2020-04-07 | — | — | CN | claimed |
| CN-110426478-A | Tonifying lung capsule quality standard promotes detection method | GUIZHOU UNIV OF TRADITIONAL CHINESE MEDICINE SECOND AFFILIATED HOSPITAL | 2019-11-08 | — | — | CN | claimed |
| CN-110123865-A | Composition comprising man and wife's grass extract | 嘉兴市爵拓科技有限公司 | 2019-08-16 | — | — | CN | claimed |
| CN-109991359-A | A kind of method of quality control of the Chinese medicine composition with cough-suppressing phlegm-dispelling functions | 苏州玉森新药开发有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-109939142-A | A kind of preparation method and its method of quality control of cudrania root granule | 安徽济人药业有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-107253955-B | The preparation method and its usage of pyrans a pair of horses going side by side benzazolyl compounds | 上海海洋大学 | 2019-04-16 | — | — | CN | claimed |
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | claimed |
| EP-0001238-B1 | HYDANTOIN DERIVATIVES, THEIR SYNTHESIS, PHARMACEUTICAL FORMULATIONS AND INTERMEDIATES IN THEIR PREPARATION | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-07-04 | — | — | EP | claimed |
| US-4420473-A | ANTHRACYCLINE, BACTERICIDES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-12-13 | — | — | US | claimed |
| EP-0048660-B1 | NEW ANTIBIOTIC SUBSTANCE, ITS PROCESS OF PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-10-12 | — | — | EP | claimed |
| US-4337262-A | HYPOTENSIVE AGENT, ANTICOAGULANT, VASODILATION, ANTIULCER AGENT, BRONCHODILATOR AGENT, ANTIALLERGEN, AND CONTRACEPTIVE | BURROUGHS WELLCOME CO. (US) | 1982-06-29 | — | — | US | claimed |
| EP-0050749-A2 | Antibiotic S/433, the process for preparing it and its use as an anti-tumor agent | GRUPPO LEPETIT S.P.A. (IT) | 1982-05-05 | — | — | EP | claimed |
| EP-0048660-A1 | New antibiotic substance, its process of production and pharmaceutical composition containing the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-03-31 | — | — | EP | claimed |
| EP-0002258-B1 | HYDANTOIN DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS AND INTERMEDIATES, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-02-17 | — | — | EP | claimed |
| EP-0001238-A1 | Hydantoin derivatives, their synthesis, pharmaceutical formulations and intermediates in their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-04-04 | — | — | EP | claimed |
| US-4147778-A | BACTERICIDES, ANTITUMOR, ANTHRACYCLINE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1979-04-03 | — | — | US | claimed |