Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8716653 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL7025787 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL28087178 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL8187512 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL59229 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL5555814 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL7183838 | 0.96 | — | — | |
| Acetic Acid SCHEMBL4097452 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL1591363 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL694363 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105477166-B | A kind of preparation method and its method of quality control of duhuo jisheng decoction granule | 广东一方制药有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-109528901-A | Red gold disappears the preparation process of sheeting | 四川维奥制药有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-109342582-A | Stop cough particle method of quality control | 广西中医药大学附属瑞康医院 | 2019-02-15 | — | — | CN | claimed |
| CN-108169403-A | A kind of quality determining method of eight-treasure soup formula particle | 广东方制药有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-108084026-A | A kind of new method of the chlorogenic acid extracting from Cortex Eucommiae | 大兴安岭林格贝寒带生物科技股份有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-107478762-B | The discriminating of children's compound the membrane of a chicken's gizzard chewable tablets and content assaying method | 河南太龙药业股份有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-107894488-A | A kind of method of quality control of concentrated type oral liquid for cough and asthma of children | 哈尔滨市康隆药业有限责任公司 | 2018-04-10 | — | — | CN | claimed |
| CN-107576751-A | The discrimination method of ginseng in ginseng antler medical liquor | 贵州信邦制药股份有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-107478762-A | The discriminating of children's compound the membrane of a chicken's gizzard chewable tablets and content assaying method | 河南太龙药业股份有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-107478749-A | A kind of detection method of the pharmaceutical preparation of Taohong Siwu Tang | 北京同仁堂科技发展股份有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-106872634-A | Facial paralysis quality determining method just scattered again | 贵阳中医学院第二附属医院 | 2017-06-20 | — | — | CN | claimed |
| CN-106770881-A | Bone aches quiet capsule quality control method | 中国人民解放军第三〇七医院 | 2017-05-31 | — | — | CN | claimed |
| CN-106198834-A | The quality of production control method of juice mended by the one seed ginseng stilbene Radix Polygoni Multiflori | 广西灵峰药业有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-103869041-B | A kind of detection method of cough-relieving combination of oral medication | 迪沙药业集团有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-105738557-A | Thin-layer chromatography detection method for icmomordin Ic in Fuyang granules | 广西壮族自治区梧州食品药品检验所 | 2016-07-06 | — | — | CN | claimed |
| CN-103059069-B | A kind of process of extracting general flavone from wild walking fern | Daxing'an Mountainrange Lin Gebei psychrophile Science and Technology Co., Ltd. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-105477166-A | Preparation method of pubescent angelica and mistletoe decoction formula granules and quality control method thereof | Guangdong yifang pharmaceutical co ltd | 2016-04-13 | — | — | CN | claimed |
| CN-104873686-A | Quality detection method for ginseng antler brain-boosting capsule | NO 2 AFFILIATED HOSPITAL GUIYANG COLLEGE TRADITIONAL CHINESE MEDICINE | 2015-09-02 | — | — | CN | claimed |
| CN-103059069-A | Novel technique method for extracting general flavone from wild walking fern | DAXINGANLING LINGONBERRY ORGANIC FOODSTUFFS CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-117866035-A | Triterpene saponin compound in golden camellia and preparation method thereof | 广西大学 | 2024-04-12 | — | — | CN | disclosed |
| US-20240016158-A1 | PLANT DISEASE CONTROL COMPOSITION COMPRISING CULTURE BROTH OF Streptomyces sp. JCK-6141 STRAIN OR EXTRACT OF CULTURE BROTH OF STRAIN, PREPARATION METHOD THEREFOR AND PLANT DISEASE CONTROL METHOD | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2024-01-18 | — | — | US | disclosed |
| EP-4245842-A1 | PLANT DISEASE CONTROL COMPOSITION COMPRISING CULTURE FLUID OF STREPTOMYCES SP. JCK-6141 STRAIN OR EXTRACT OF CULTURE FLUID OF STRAIN, PREPARATION METHOD THEREFOR AND PLANT DISEASE CONTROL METHOD | Industry Foundation of Chonnam National University (KR) | 2023-09-20 | — | — | EP | disclosed |
| CN-113402518-B | Imidazo [4,5-c ] ring compounds containing substituted guanidine groups | 3M创新有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2023085926-A1 | DGAT1/2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS (DIESL) | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis (NL) | 2023-05-19 | — | — | WO | disclosed |
| EP-3344622-B1 | GUANIDINE SUBSTITUTED, FUSED 1H-IMIDAZO[4,5-C]PYRIDINE COMPOUNDS USEFUL IN THE TREATMENT OF VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES CO (US) | 2021-07-07 | — | — | EP | disclosed |
| EP-3344623-B1 | IMIDAZO[4,5-C]RING COMPOUNDS CONTAINING SUBSTITUTED GUANIDINE GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20200319152-A1 | THIN-LAYER CHROMATOGRAPHY SYSTEM AND METHOD FOR ASSESSING ANALYTE CONCENTRATIONS IN SAMPLES | UCL BUSINESS LTD (GB) | 2020-10-08 | — | — | US | disclosed |
| US-10487081-B2 | Guanidine substituted imidazo[4,5-c] ring compounds | 3M INNOVATION PROPERTIES COMPANY (US) | 2019-11-26 | — | — | US | disclosed |
| CN-110464768-A | A kind of Chinese medicinal capsule and preparation method thereof for treating diabetic retinopathy | XU YANQUN | 2019-11-19 | — | — | CN | disclosed |
| CN-105477166-B | A kind of preparation method and its method of quality control of duhuo jisheng decoction granule | 广东一方制药有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-110031401-A | A kind of method for quick identification of Radix Notoginseng powder | 云三七(深圳)大数据科技有限责任公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109613165-A | A kind of Jinshuibao gold size capsule qualitative checking method | 江西省药明扬海医药科技有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109528901-A | Red gold disappears the preparation process of sheeting | 四川维奥制药有限公司 | 2019-03-29 | — | — | CN | disclosed |
| EP-2397488-B1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | FEDERAL STATE BUDGETARY INSTITUTION RES ZAKUSOV INSTITUTE OF PHARMACOLOGY (RU) | 2019-03-27 | — | — | EP | disclosed |
| US-20190055241-A1 | GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2019-02-21 | — | — | US | disclosed |
| CN-109342582-A | Stop cough particle method of quality control | 广西中医药大学附属瑞康医院 | 2019-02-15 | — | — | CN | disclosed |
| CN-109045231-A | A kind of loquat dew and preparation method thereof | 华润三九（雅安）药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-10150768-B2 | Guanidine substituted imidazo[4,5-c] ring compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-12-11 | — | — | US | disclosed |
| US-10118925-B2 | Imidazo[4,5-c] ring compounds containing substituted guanidine groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-11-06 | — | — | US | disclosed |
| US-20180244669-A1 | IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING SUBSTITUTED GUANIDINE GROUPS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2018-08-30 | — | — | US | disclosed |
| US-20180237435-A1 | GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2018-08-23 | — | — | US | disclosed |
| EP-3344623-A1 | IMIDAZO[4,5-c]RING COMPOUNDS CONTAINING SUBSTITUTED GUANIDINE GROUPS | 3M Innovative Properties Company (US) | 2018-07-11 | — | — | EP | disclosed |
| EP-3344622-A1 | GUANIDINE SUBSTITUTED IMIDAZO[4,5-c]RING COMPOUNDS | 3M Innovative Properties Company (US) | 2018-07-11 | — | — | EP | disclosed |
| CN-108169403-A | A kind of quality determining method of eight-treasure soup formula particle | 广东方制药有限公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-108084026-A | A kind of new method of the chlorogenic acid extracting from Cortex Eucommiae | 大兴安岭林格贝寒带生物科技股份有限公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-107478762-B | The discriminating of children's compound the membrane of a chicken's gizzard chewable tablets and content assaying method | 河南太龙药业股份有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-108042590-A | A kind of residual extract of Radix Ginseng stem and leaf of low agriculture and preparation method thereof | 杨凌萃健生物工程技术有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-108026092-A | Imidazo [4,5-c] cycle compound of guanidine substitution | 3M创新有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107998305-A | A kind of Chinese medicine preparation for being used to treat coronary heart disease | 安徽省纽斯康生物工程有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-107922416-A | Imidazo [4,5-c ] ring compounds containing substituted guanidine groups | 3M创新有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107894488-A | A kind of method of quality control of concentrated type oral liquid for cough and asthma of children | 哈尔滨市康隆药业有限责任公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-107576751-A | The discrimination method of ginseng in ginseng antler medical liquor | 贵州信邦制药股份有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-107478749-A | A kind of detection method of the pharmaceutical preparation of Taohong Siwu Tang | 北京同仁堂科技发展股份有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-107478762-A | The discriminating of children's compound the membrane of a chicken's gizzard chewable tablets and content assaying method | 河南太龙药业股份有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-107064090-A | A kind of quality determining method of sinew-Soothing Blood-Quickening Tablet | 黑龙江葵花药业股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-107028994-A | The direct oral traditional Chinese medicine medicine materical crude slice of Radix Notoginseng powder | 江苏苏轩堂药业有限公司 | 2017-08-11 | — | — | CN | disclosed |
| US-9683014-B2 | Dipeptide mimetics of NGF and BDNF neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2017-06-20 | — | — | US | disclosed |
| CN-106872634-A | Facial paralysis quality determining method just scattered again | 贵阳中医学院第二附属医院 | 2017-06-20 | — | — | CN | disclosed |
| CN-106770881-A | Bone aches quiet capsule quality control method | 中国人民解放军第三〇七医院 | 2017-05-31 | — | — | CN | disclosed |
| CN-106771014-A | The quality standard and manufacturing process of the pseudo-ginseng qualitative, quantitative prepared slices of Chinese crude drugs | 广州今典精方药业有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106706766-A | Method for detecting newly increased detection components in traditional Chinese medicinal Tang Herb for treating AIDS | 上海百岁行药业有限公司 | 2017-05-24 | — | — | CN | disclosed |
| WO-2017040233-A1 | GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017040234-A1 | IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING SUBSTITUTED GUANIDINE GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |
| CN-106198834-A | The quality of production control method of juice mended by the one seed ginseng stilbene Radix Polygoni Multiflori | 广西灵峰药业有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-103869041-B | A kind of detection method of cough-relieving combination of oral medication | 迪沙药业集团有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105797005-A | Traditional Chinese medicine composition for treating hysteromyoma | 宋毅 | 2016-07-27 | — | — | CN | disclosed |
| CN-105738557-A | Thin-layer chromatography detection method for icmomordin Ic in Fuyang granules | 广西壮族自治区梧州食品药品检验所 | 2016-07-06 | — | — | CN | disclosed |
| CN-103059069-B | A kind of process of extracting general flavone from wild walking fern | Daxing'an Mountainrange Lin Gebei psychrophile Science and Technology Co., Ltd. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-105477166-A | Preparation method of pubescent angelica and mistletoe decoction formula granules and quality control method thereof | Guangdong yifang pharmaceutical co ltd | 2016-04-13 | — | — | CN | disclosed |
| CN-102365294-B | The dipeptide analogue of neurotrophic factor NGF and BDNF | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUKNAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2016-02-17 | — | — | CN | disclosed |
| CN-104873686-A | Quality detection method for ginseng antler brain-boosting capsule | NO 2 AFFILIATED HOSPITAL GUIYANG COLLEGE TRADITIONAL CHINESE MEDICINE | 2015-09-02 | — | — | CN | disclosed |
| US-20150166594-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII (RU) | 2015-04-23 | — | — | US | disclosed |
| CN-104367729-A | Preparation method of traditional Chinese compound preparation pachyrhizua angulatus and hawthorn lipid lowering granule | XIAO JUNPING | 2015-02-25 | — | — | CN | disclosed |
| US-20130302247-A1 | SYNTHESIS OF FLUOROARACHIDONIC ACID AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2013-11-14 | — | — | US | disclosed |
| CN-103059069-A | Novel technique method for extracting general flavone from wild walking fern | DAXINGANLING LINGONBERRY ORGANIC FOODSTUFFS CO LTD | 2013-04-24 | — | — | CN | disclosed |
| CN-102365294-A | Dipeptide mimetics of ngf and bdnf neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK | 2012-02-29 | — | — | CN | disclosed |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2011-12-22 | — | — | US | disclosed |
| EP-2397488-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | Uchrezhdenie Rossiiskoi Akademii Meditsynskikh Nauk Nauchno-issledovatelsky Institut Farmakologii Imeni V.V.Zakusova Ramn (RU) | 2011-12-21 | — | — | EP | disclosed |
| US-8076496-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110236930-A1 | CHEMOSELECTIVE LIGATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-29 | — | — | US | disclosed |
| US-7973143-B2 | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2011-07-05 | — | — | US | disclosed |
| US-7939626-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-05-10 | — | — | US | disclosed |
| CN-101386591-B | Lamellarins alkaloid and preparation method and use in anti-hiv thereof | UNIV BEIJING | 2011-05-04 | — | — | CN | disclosed |
| US-7923582-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-04-12 | — | — | US | disclosed |
| US-7838665-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-11-23 | — | — | US | disclosed |
| US-7820627-B2 | Lipid A and other carbohydrate ligand analogs | ONCOTHYREON INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7667012-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product; N-azidogalactosamine | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-23 | — | — | US | disclosed |
| EP-1027443-B1 | SPHINGOSINE-1-PHOSPHATE LYASE POLYPEPTIDES, POLYNUCLEOTIDES AND MODULATING AGENTS AND METHODS OF USE THEREFOR | CHILDRENS HOSP MEDICAL CENTER (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20090203044-A1 | SPHINGOSINE-1-PHOSPHATE LYASE POLYPEPTIDES, POLYNUCLEOTIDES AND MODULATING AGENTS AND METHODS OF USE THEREFOR | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2009-08-13 | — | — | US | disclosed |
| CN-100515445-C | Quality control method for traditional Chinese medicine preparation for treating generalized anxiety | GUIZHOU TONGJITANG PHARMACEUTI (CN) | 2009-07-22 | — | — | CN | disclosed |
| CN-101386591-A | Lamellarins alkaloid and and preparation method and use in anti-hiv thereof | UNIV BEIJING (CN) | 2009-03-18 | — | — | CN | disclosed |
| US-7491707-B1 | Synthetic lipid-a-analogs and uses thereof | BIOMIRA, INC. (CA) | 2009-02-17 | — | — | US | disclosed |
| US-20080214801-A1 | CHEMOSELECTIVE LIGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-04 | — | — | US | disclosed |
| EP-0958305-B1 | INHIBITIONS OF THE INTERACTION BETWEEN P53 AND MDM2 | CANCER REC TECH LTD (GB) | 2008-06-04 | — | — | EP | disclosed |
| US-20080085995-A1 | SPHINGOSINE-1-PHOSPHATE LYASE POLYPEPTIDES, POLYNUCLEOTIDES AND MODULATING AGENTS AND METHODS OF USE THEREFOR | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2008-04-10 | — | — | US | disclosed |
| US-7262044-B2 | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2007-08-28 | — | — | US | disclosed |
| US-20070092503-A1 | Human alkaline sphingomyelinase and use thereof | SKANE-MEJERIER EK. FOR. (SE) | 2007-04-26 | — | — | US | disclosed |
| WO-2007025304-A2 | PROCESS FOR PREPARING SACCHARINIC ACIDS AND LACTONES | THE CHANCELLORS, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2007-03-01 | — | — | WO | disclosed |
| US-20070037964-A1 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-15 | — | — | US | disclosed |
| US-20060276658-A1 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-12-07 | — | — | US | disclosed |
| US-7122703-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-17 | — | — | US | disclosed |
| CN-1843432-A | Quality control method for traditional Chinese medicine formulation for treating generalized anxiety | GUIZHOU TONGJITANG PHARMACEUTI (CN) | 2006-10-11 | — | — | CN | disclosed |
| US-7083983-B2 | Inhibitors of the interaction between P53 and MDM2 | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (CH) | 2006-08-01 | — | — | US | disclosed |
| EP-1263771-B1 | CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE | UNIV CALIFORNIA (US) | 2006-06-14 | — | — | EP | disclosed |
| US-7041291-B2 | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2006-05-09 | — | — | US | disclosed |
| US-20060040891-A1 | Lipid a and other carbohydrate ligand analogs | BIOMIRA, INC (CA) | 2006-02-23 | — | — | US | disclosed |
| EP-1618192-A1 | HUMAN ALKALINE SPHINGOMYELINASE AND USE THEREOF | Skanemejerier Ek.För. (SE) | 2006-01-25 | — | — | EP | disclosed |
| US-20050245432-A1 | N-methyl amino acids | UBIQUITOUS TECHNOLOGIES PTY. LTD. (AU) | 2005-11-03 | — | — | US | disclosed |
| US-20050221346-A1 | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor | CHILDREN'S HOSPITAL & REAEARCH INSTITUTE AT OAKLAND (US) | 2005-10-06 | — | — | US | disclosed |
| CN-1213144-C | Recombination nucleic acid molecule and application thereof | REGENT OF UNIV OF CALIFORNIA (US) | 2005-08-03 | — | — | CN | disclosed |
| US-20050148032-A1 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-07-07 | — | — | US | disclosed |
| US-20050137137-A1 | Inhibitors of the Interaction between p53 and MDM2 | LANE DAVID P (GB) | 2005-06-23 | — | — | US | disclosed |
| US-6830881-B2 | Diagnosis, therapy cancer; genetic engineering | CHILDREN'S HOSPITAL & RESEARCH INSTITUTE AT OAKLAND | 2004-12-14 | — | — | US | disclosed |
| WO-2004094629-A1 | HUMAN ALKALINE SPHINGOMYELINASE AND USE THEREOF | SKÅNEMEJERIER EK. FÖR. (SE) | 2004-11-04 | — | — | WO | disclosed |
| US-20040047851-A1 | Method for treating a subject suffering from conditions associated with an extracellular zinc sphingomyelinase | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2004-03-11 | — | — | US | disclosed |
| US-20030199084-A1 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-10-23 | — | — | US | disclosed |
| US-20030166897-A1 | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | 2003-09-04 | — | — | US | disclosed |
| US-6613322-B2 | Administering enzyme inhibitors | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-09-02 | — | — | US | disclosed |
| US-6570040-B2 | Condensation of specifically engineered phosphine which can provide for formation of amide bond between two reactive partners resulting in product comprising a phosphine moiety or which can be engineered to comprise a cleavable linker | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-05-27 | — | — | US | disclosed |
| US-6569666-B1 | For use in the detection and treatment of breast cancer | CHILDREN'S HOSPITAL OAKLAND RESEARCH INSTITUTE | 2003-05-27 | — | — | US | disclosed |
| US-20030092050-A1 | Lipid A 4' kinase | DUKE UNIVERSITY | 2003-05-15 | — | — | US | disclosed |
| US-20030059922-A1 | Sphingosine1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | 2003-03-27 | — | — | US | disclosed |
| US-20030026796-A1 | Method for treating a subject suffering from conditions associated with an extracellular zinc sphingomyelinase | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-02-06 | — | — | US | disclosed |
| US-6495359-B1 | TO DIAGNOSE AND/OR TREAT CANCERS SUCH AS BREAST CANCER; NUCLEOTIDE SEQUENCES | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA | 2002-12-17 | — | — | US | disclosed |
| EP-1263771-A2 | CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-12-11 | — | — | EP | disclosed |
| US-6465631-B1 | TO A NUCLEIC ACID ENCODING LIPID A 4' KINASE AND TO A METHOD OF PRODUCING LIPID A 4' KINASE RECOMBINANTLY USING SAME. THE INVENTION FURTHER RELATES TO METHODS OF PRODUCING 4' PHOSPHORYLATED LIPID A ANALOGS USING THE RECOMBINANTLY | DUKE UNIVERSITY | 2002-10-15 | — | — | US | disclosed |
| US-6423527-B1 | ISOLATED POLYNUCLEOTIDE COMPRISING SPECIFIED NUCLEOTIDE SEQUENCES, SEQUENCES THAT HYBRIDIZE TO COMPLEMENTARY POLYNUCLEOTIDES, OR SEQUENCES THAT ENCODE POLYPEPTIDE HAVING SPHINGOSINE-1-PHOSPHATE LYASE ACTIVITY | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA | 2002-07-23 | — | — | US | disclosed |
| US-20020016003-A1 | Chemoselective ligation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-02-07 | — | — | US | disclosed |
| WO-2001068565-A2 | CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-09-20 | — | — | WO | disclosed |
| US-20010018511-A1 | Anticancer agent | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2001-08-30 | — | — | US | disclosed |
| CN-1066731-C | Substrates for beta-lactamases and uses thereof | UNIV CALIFORNIA (US) | 2001-06-06 | — | — | CN | disclosed |
| CN-1296078-A | Recombination nucleic acid molecule and application thereof | REGENT OF UNIV OF CALIFORNIA (US) | 2001-05-23 | — | — | CN | disclosed |
| CN-1061035-C | Phenylalkanolamine derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-24 | — | — | CN | disclosed |
| EP-1027443-A2 | SPHINGOSINE-1-PHOSPHATE LYASE POLYPEPTIDES, POLYNUCLEOTIDES AND MODULATING AGENTS AND METHODS OF USE THEREFOR | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA (US) | 2000-08-16 | — | — | EP | disclosed |
| US-6001626-A | HEAT RESISTANT PHOSPHOLIPASE USEFUL IN REFINING OIL AND DRUG DEVELOPMENT | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1999-12-14 | — | — | US | disclosed |
| EP-0958305-A2 | INHIBITIONS OF THE INTERACTION BETWEEN P53 AND MDM2 | Novartis AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999016888-A2 | SPHINGOSINE-1-PHOSPHATE LYASE POLYPEPTIDES, POLYNUCLEOTIDES AND MODULATING AGENTS AND METHODS OF USE THEREFOR | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHEN CALIFORNIA (US) | 1999-04-08 | — | — | WO | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| CN-1184479-A | Substrates for beta-lactamases and uses thereof | UNIV CALIFORNIA (US) | 1998-06-10 | — | — | CN | disclosed |
| EP-0624163-B1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMA (IT) | 1998-03-25 | — | — | EP | disclosed |
| WO-1998001467-A2 | INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2 | NOVARTIS AG (CH) | 1998-01-15 | — | — | WO | disclosed |
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |
| WO-1997007131-A1 | ACYLATED OLIGOPEPTIDES CONTAINING PHOSPHOTYROSINE AS INHIBITORS OF PROTEIN TYROSINE KINASES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |
| EP-0407390-B1 | BIOCOMPATIBLE COATINGS | BSI CORP (US) | 1996-04-24 | — | — | EP | disclosed |
| US-5501980-A | Benzazolylcoumarin-based ion indicators | MOLECULAR PROBES, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5492896-A | TREATING CYTOMEGALO VIRUS INFECTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0376518-B1 | Phospholipid nucleosides | LILLY CO ELI (US) | 1995-11-29 | — | — | EP | disclosed |
| CN-1105990-A | Phenylalkanolamine derivatives | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |
| EP-0648744-A1 | Phenylalkanolamine derivatives as antagonists of the NMDA receptor | F. HOFFMANN-LA ROCHE AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0624163-A1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1994-11-17 | — | — | EP | disclosed |
| CN-1087625-A | N-(hydroxyethyl) succinic diamide derivative | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-06-08 | — | — | CN | disclosed |
| US-5308766-A | Hydrolytic enzyme inhibitors/inactivators and methods for using same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-05-03 | — | — | US | disclosed |
| WO-1993015106-A1 | CYCLIC CALCITONINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1993-08-05 | — | — | WO | disclosed |
| US-5210193-A | Bactericide | AMERICAN CYANAMID COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0231919-B1 | N-HETEROCYCLIC ALCOHOL RENIN INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5132320-A | Polyunsaturated 2,8-dioxabicyclo/3.2.1/octanetricarboxylates, use to treat hypercholesterolemia | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0477739-A2 | Glycosyl-Phosphatidylinositol-Specific Phospholipase D | F. HOFFMANN-LA ROCHE AG (CH) | 1992-04-01 | — | — | EP | disclosed |
| EP-0407390-A4 | BIOCOMPATIBLE COATINGS | — | 1991-12-11 | — | — | EP | disclosed |
| US-5055487-A | Novel anti-fungal compounds | MERCK & CO., INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0448393-A1 | Antihypercholesterolemics | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0407390-A1 | BIOCOMPATIBLE COATINGS. | BIO METRIC SYSTEMS INC (US) | 1991-01-16 | — | — | EP | disclosed |
| US-4940710-A | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4931444-A | FOR LEUKOTRIENE-MEDIATED DISEASES AND DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-05 | — | — | US | disclosed |
| US-4885292-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-12-05 | — | — | US | disclosed |
| WO-1989005616-A1 | BIOCOMPATIBLE COATINGS | BIO-METRIC SYSTEMS, INC. (US) | 1989-06-29 | — | — | WO | disclosed |
| US-4812442-A | TREATMENT OF HYPERTENSION, CONCESTIVE HEART FAILURE | MERCK & CO., INC. (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0171677-B1 | NOVEL ANTHRACYCLINE ANTIBIOTICS | Sanraku Incorporated (JP) | 1988-11-30 | — | — | EP | disclosed |
| US-4788182-A | VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4782043-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1988-11-01 | — | — | US | disclosed |
| US-4743584-A | C-terminal amide cyclic renin inhibitors containing peptide isosteres | MERCK & CO., INC. (US) | 1988-05-10 | — | — | US | disclosed |
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0231919-A2 | N-Heterocyclic alcohol renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-08-12 | — | — | EP | disclosed |
| EP-0230053-A2 | 7-(Substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4668663-A | TREATMENT OF HYPERTENSION AND HYPERALDOSTERONISM | MERCK & CO., INC. (US) | 1987-05-26 | — | — | US | disclosed |
| US-4665052-A | HOMOPHENYLALANINE, HYPOTENSIVES, ANTIALDOSTERONES | MERCK & CO., INC. (US) | 1987-05-12 | — | — | US | disclosed |
| US-4665193-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1987-05-12 | — | — | US | disclosed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | disclosed |
| US-4629724-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4616088-A | Amino acid ester and amide renin inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1986-10-07 | — | — | US | disclosed |
| US-4612371-A | Anthracycline antibiotics | SANRAKU INCORPORATED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0181071-A2 | Amino acid ester and amide renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1986-05-14 | — | — | EP | disclosed |
| EP-0171677-A1 | Novel anthracycline antibiotics | Sanraku Incorporated (JP) | 1986-02-19 | — | — | EP | disclosed |
| US-4548923-A | IMMUNOSTIMULANTS, BACTERICIDES, VIRICIDES | CIBA GEIGY CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0156319-A2 | Renin inhibitors containing homophe 8 | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0156320-A2 | Renin inhibitors containing homophe 8 and a C-terminal amide cycle | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0129189-A2 | Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4485099-A | HYPOTENSIVE AGENTS/,ANTIALDOSTERONES | MERCK & CO., INC. (US) | 1984-11-27 | — | — | US | disclosed |
| US-4477441-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1984-10-16 | — | — | US | disclosed |
| US-4477440-A | HYPERTENSIVE AGENTS; HYPERALDOSTERONISM; MEDICAL DIAGNOSIS; CYCLIC POLYPEPTIDES | MERCK & CO., INC. (US) | 1984-10-16 | — | — | US | disclosed |
| US-4439425-A | IMMUNOLOGY | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0026849-B1 | PROCESS FOR PRODUCING ANTHRACYCLINE GLYCOSIDES | SANRAKU-OCEAN CO., LTD. (JP) | 1983-12-07 | — | — | EP | disclosed |
| US-4405607-A | Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use | SANDOZ LTD. (CH) | 1983-09-20 | — | — | US | disclosed |
| US-4368194-A | ANTIINFLAMMATORY, ANTIARTHRITIC | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1983-01-11 | — | — | US | disclosed |
| US-4337312-A | CONVERSION OF AKLAVINONE AND RHODOMYCINONE TO DAUNOMYCIN AND BAUMYCIN ANTIBIOTICS | SANRAKU-OCEAN CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0044451-A1 | Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use | SANDOZ AG (CH) | 1982-01-27 | — | — | EP | disclosed |
| US-4312989-A | Pharmacologically active amine boranes | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0026849-A1 | Process for producing anthracycline glycosides | SANRAKU-OCEAN CO., LTD. (JP) | 1981-04-15 | — | — | EP | disclosed |
| US-4128540-A | Pyroglutamyl-histidyl-tryptophanyl-seryl-tyrosyl hydrazides | PARKE, DAVIS & COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-3963691-A | POLYPEPTIDES, PEPTIZATION | MERCK & CO., INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963691-A | POLYPEPTIDES, PEPTIZATION | MERCK & CO., INC. (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (20 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166594-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | MSN, MGAM, NISCH | FFAR3 4553/4885LCK 4063/4885FYN 4024/4885 |
| US-20020016003-A1 | Chemoselective ligation | PTMS, QPCT, DNPEP | FFAR3 2410/4885LCK 975/4885FYN 849/4885 |
| US-20050245432-A1 | N-methyl amino acids | VIP, NPPA, PTMS | FFAR3 2142/4885LCK 1339/4885FYN 2075/4885 |
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | FFAR3 889/4885LCK 504/4885FYN 276/4885 |
| US-10150768-B2 | Guanidine substituted imidazo[4,5-c] ring compounds | IFNG, IL4, IRF3 | FFAR3 3461/4885LCK 1832/4885FYN 3975/4885 |
| US-10487081-B2 | Guanidine substituted imidazo[4,5-c] ring compounds | IFNG, IRF3, IL4 | FFAR3 3691/4885LCK 1618/4885FYN 3874/4885 |
| US-10118925-B2 | Imidazo[4,5-c] ring compounds containing substituted guanidine groups | IFNG, IRF3, IL4 | FFAR3 3727/4885LCK 1431/4885FYN 3899/4885 |
| US-20060276658-A1 | Chemoselective ligation | PTMS, PGF, ACSL3 | FFAR3 2422/4885LCK 2542/4885FYN 1065/4885 |
| US-20110236930-A1 | CHEMOSELECTIVE LIGATION | PTMS, QPCT, DNPEP | FFAR3 2410/4885LCK 975/4885FYN 849/4885 |
| US-20180244669-A1 | IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING SUBSTITUTED GUANIDINE GROUPS | IFNG, IRF3, IL4 | FFAR3 3727/4885LCK 1431/4885FYN 3899/4885 |
| US-20030199084-A1 | Chemoselective ligation | PTMS, QPCT, DNPEP | FFAR3 2410/4885LCK 975/4885FYN 849/4885 |
| US-20240016158-A1 | PLANT DISEASE CONTROL COMPOSITION COMPRISING CULTURE BROTH OF Streptomyces sp. JCK-6141 STRAIN OR EXTRACT OF CULTURE BROTH OF STRAIN, PREPARATION METHOD THEREFOR AND PLANT DISEASE CONTROL METHOD | ITK, WASF2, WEE1 | FFAR3 4351/4885LCK 3138/4885FYN 3709/4885 |
| US-20070037964-A1 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | PTMS, PHOSPHO1, QPCT | FFAR3 3576/4885LCK 1936/4885FYN 1630/4885 |
| US-20080214801-A1 | CHEMOSELECTIVE LIGATION | PTMS, QPCT, DNPEP | FFAR3 2410/4885LCK 975/4885FYN 849/4885 |
| US-20050148032-A1 | Chemoselective ligation | PTMS, QPCT, DNPEP | FFAR3 2410/4885LCK 975/4885FYN 849/4885 |
| US-20060040891-A1 | Lipid a and other carbohydrate ligand analogs | SELPLG, STT3A, LY96 | FFAR3 75/4885LCK 750/4885FYN 954/4885 |
| US-20130302247-A1 | SYNTHESIS OF FLUOROARACHIDONIC ACID AND METHODS OF USE THEREOF | ALOX15B, ALOX15, ALOX5 | FFAR3 81/4885LCK 3429/4885FYN 780/4885 |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | FFAR3 889/4885LCK 504/4885FYN 276/4885 |
| US-20190055241-A1 | GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS | IFNG, IRF3, IL4 | FFAR3 3691/4885LCK 1618/4885FYN 3874/4885 |
| US-20180237435-A1 | GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS | IFNG, IL4, IRF3 | FFAR3 3461/4885LCK 1832/4885FYN 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.