Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1615802 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL7025787 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL28087178 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL8187512 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL59229 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL5555814 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL7183838 | 0.96 | — | — | |
| Acetic Acid SCHEMBL4097452 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL1591363 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNAALDH1A1 | |
| Acetic Acid SCHEMBL694363 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843735-A | Aklavinone C-11 hydroxylase, gene coding for same, expression vector therefor, and process for preparing hybrid antibiotics by using said vector | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-12-01 | — | — | US | disclosed |