Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.66 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702756 | 0.80 | TAS1R3 (1.00) | TAS1R3TAS1R1POLBMAPK1ALDH1A1 | |
| SCHEMBL703261 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1POLBMAPK1KDM4E | |
| SCHEMBL11918676 | 0.78 | TAS1R3 (0.71) | TAS1R3TAS1R1POLBMAPK1ALDH1A1 | |
| SCHEMBL702640 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1POLBMAPK1ALDH1A1 | |
| SCHEMBL5923949 | 0.77 | TAS1R3 (0.69) | TAS1R3TAS1R1POLBMAPK1ALDH1A1 | |
| SCHEMBL14537867 | 0.76 | TAS1R3 (0.81) | TAS1R3TAS1R1POLBMAPK1ALDH1A1 | |
| SCHEMBL5923939 | 0.76 | TAS1R3 (0.68) | TAS1R3TAS1R1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1205862 | 0.75 | MAPK1 (0.61) | MAPK1ALDH1A1GAAHPGD | |
| SCHEMBL27490830 | 0.74 | CYP1A2 (0.48) | POLBMAPK1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL19987404 | 0.74 | TAS1R3 (0.89) | TAS1R3TAS1R1POLBMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |