Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.69 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702756 | 0.82 | TAS1R3 (1.00) | TAS1R3TAS1R1MEN1KMT2APOLB | |
| SCHEMBL703261 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1POLBMAPTRAB9A | |
| SCHEMBL702640 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1MEN1KMT2APOLB | |
| SCHEMBL11918676 | 0.81 | TAS1R3 (0.71) | TAS1R3TAS1R1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5923939 | 0.78 | TAS1R3 (0.68) | TAS1R3TAS1R1POLBMAPTRAB9A | |
| SCHEMBL14537867 | 0.78 | TAS1R3 (0.81) | TAS1R3TAS1R1MEN1KMT2APOLB | |
| SCHEMBL5923947 | 0.77 | TAS1R3 (0.66) | TAS1R3TAS1R1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5923969 | 0.77 | KMT2A (0.59) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL13480583 | 0.76 | KMT2A (0.63) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL19987404 | 0.76 | TAS1R3 (0.89) | TAS1R3TAS1R1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |