SCHEMBL5923965

SCHEMBL5923965

COc1ccccc1NC(=O)NC(C(C)C)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.63
LPAR1 Q92633 1/20 0.59
ALDH1A1 P00352 3/20 0.59
POLB P06746 2/20 0.57
MAPT P10636 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
KDM4E B2RXH2 1/20 0.54
GAA P10253 1/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449467 0.87 ANPEP (0.66) ANPEPLPAR1ALDH1A1POLBMAPT
Benzene SCHEMBL11580795 0.86 ANPEP (0.64) ANPEPLPAR1ALDH1A1POLBMAPT
SCHEMBL31040567 0.83 POLB (0.77) LPAR1ALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL4554983 0.83 POLB (0.77) LPAR1ALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL3064292 0.82 ANPEP (0.64) ANPEPLPAR1ALDH1A1POLBMAPT
SCHEMBL5923961 0.81 LPAR1 (0.62) LPAR1ALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL13596172 0.80 POLB (0.62) ANPEPLPAR1ALDH1A1POLBMAPT
SCHEMBL6348301 0.79 POLB (0.61) ANPEPLPAR1ALDH1A1POLBMAPT
SCHEMBL11580793 0.79 NPC1 (0.63) ANPEPLPAR1ALDH1A1POLBMAPT
SCHEMBL13923626 0.78 SMN1; SMN2 (0.68) LPAR1ALDH1A1POLBMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060045953-A1 Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers SENOMYX, INC. 2006-03-02 US disclosed