SCHEMBL31040567

SCHEMBL31040567

COc1ccccc1NC(=O)Nc1ccccc1OC

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.77
SMN1; SMN2 Q16637 4/20 0.75
MAPT P10636 4/20 0.75
RAB9A P51151 3/20 0.75
NPC1 O15118 2/20 0.75
ALDH1A1 P00352 4/20 0.74
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
HPGD P15428 2/20 0.71
KDM4E B2RXH2 1/20 0.71
GAA P10253 1/20 0.71
HSD17B10 Q99714 1/20 0.71
HTT P42858 1/20 0.71
LPAR1 Q92633 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
AHR P35869 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4554983 1.00 POLB (0.77) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL13923626 0.90 SMN1; SMN2 (0.68) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL23331399 0.89 ALDH1A1 (0.66) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL9036508 0.89 ALDH1A1 (0.71) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL7759449 0.89 ALDH1A1 (0.66) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL1463287 0.88 GRIK1 (0.72) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL6850954 0.88 ALDH1A1 (0.71) POLBSMN1; SMN2MAPTRAB9ANPC1
Hydrochloric Acid SCHEMBL9004628 0.87 ALDH1A1 (0.69) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL18120560 0.87 MEN1 (0.75) POLBSMN1; SMN2MAPTRAB9ANPC1
SCHEMBL11006683 0.87 RAB9A (0.78) POLBSMN1; SMN2MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118684599-A Preparation method of N, N-diaryl urea compound 上海应用技术大学 2024-09-24 CN disclosed