Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.83 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.83 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.83 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.83 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.78 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064349 | 1.00 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL2064346 | 1.00 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923942 | 0.93 | TAS1R3 (0.74) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923946 | 0.93 | TAS1R3 (0.74) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923955 | 0.88 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923928 | 0.88 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923930 | 0.88 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL705805 | 0.87 | TAS1R3 (1.00) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923966 | 0.87 | TAS1R3 (0.70) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923964 | 0.87 | TAS1R3 (0.70) | PDE4APDE4BPDE4CPDE4DTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |