Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.83 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.83 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.83 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.83 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.78 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064349 | 1.00 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923976 | 1.00 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923942 | 0.93 | TAS1R3 (0.74) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923946 | 0.93 | TAS1R3 (0.74) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923955 | 0.88 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923928 | 0.88 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923930 | 0.88 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL705805 | 0.87 | TAS1R3 (1.00) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923966 | 0.87 | TAS1R3 (0.70) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5923964 | 0.87 | TAS1R3 (0.70) | PDE4APDE4BPDE4CPDE4DTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | claimed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | claimed |
| EP-3398452-B1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS | FIRMENICH INCORPORATED (US) | 2024-10-02 | — | — | EP | disclosed |
| EP-3398452-A2 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | Senomyx, Inc. (US) | 2018-11-07 | — | — | EP | disclosed |
| EP-3235811-B1 | PROCESS OF PREPARING OXALAMIDES | SENOMYX INC (US) | 2018-07-25 | — | — | EP | disclosed |
| EP-3235811-A1 | PROCESS OF PREPARING OXALAMIDES | Senomyx, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-2010009-B1 | PROCESSES FOR PREPARING SOLID FLAVORANT COMPOSITIONS | SENOMYX INC (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9072313-B2 | Comestible compositions comprising high potency savory flavorants, and processes for producing them | SENOMYX, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130266708-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. (US) | 2013-10-10 | — | — | US | disclosed |
| US-8318947-B2 | Comestible compositions comprising high potency savory flavorants, and processes for producing them | SENOMYX, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120226047-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-8148536-B2 | Comestible compositions comprising high potency savory flavorants, and processes for producing them | SENOMYX, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20090280230-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. | 2009-11-12 | — | — | US | disclosed |
| EP-2010009-A2 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | Senomyx, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007124152-A2 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. (US) | 2007-11-01 | — | — | WO | disclosed |
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226047-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | TAS1R1, TAS1R2, TAS2R50 | PDE4A 2445/4885PDE4B 2499/4885PDE4C 2869/4885 |
| US-20090280230-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | TAS1R1, TAS1R2, GRM1 | PDE4A 2530/4885PDE4B 2563/4885PDE4C 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.