Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927597 | 0.90 | MMP12 (0.50) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5926559 | 0.90 | TACR3 (0.51) | TACR3DCAF1ALDH1A1NPC1HPGD | |
| SCHEMBL5926460 | 0.89 | TACR3 (0.53) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5927335 | 0.88 | TACR3 (0.51) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5927088 | 0.88 | TACR3 (0.51) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5926526 | 0.88 | TACR3 (0.51) | TACR3DCAF1UTS2R | |
| SCHEMBL5927319 | 0.88 | TACR3 (0.51) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5926760 | 0.88 | TACR3 (0.51) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5927139 | 0.87 | UTS2R (0.45) | MEN1KMT2ATACR3DCAF1ALDH1A1 | |
| SCHEMBL5926414 | 0.87 | TACR3 (0.50) | MEN1KMT2ATACR3ALDH1A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | MEN1 3448/4885KMT2A 2112/4885TACR3 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.