Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
| ▸ | DCAF1 | Q9Y4B6 | 5/20 | 0.49 |
| ▸ | CTSA | P10619 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927319 | 0.94 | TACR3 (0.51) | TACR3DCAF1CTSAKDM4EALDH1A1 | |
| SCHEMBL5927335 | 0.94 | TACR3 (0.51) | TACR3DCAF1CTSAKDM4EALDH1A1 | |
| SCHEMBL4831636 | 0.90 | DCAF1 (0.51) | TACR3DCAF1CTSAKDM4EALDH1A1 | |
| SCHEMBL5926404 | 0.90 | TACR3 (0.49) | TACR3DCAF1CTSAKDM4EALDH1A1 | |
| SCHEMBL5926314 | 0.89 | MEN1 (0.53) | TACR3DCAF1KDM4EALDH1A1LMNA | |
| SCHEMBL5926926 | 0.89 | TACR3 (0.48) | TACR3DCAF1CTSAKDM4EALDH1A1 | |
| SCHEMBL5926414 | 0.89 | TACR3 (0.50) | TACR3CTSAKDM4EALDH1A1LMNA | |
| SCHEMBL6099233 | 0.89 | PIN1 (0.49) | TACR3CTSAROCK2ROCK1 | |
| SCHEMBL5927597 | 0.88 | MMP12 (0.50) | TACR3DCAF1KDM4EALDH1A1LMNA | |
| SCHEMBL5926559 | 0.88 | TACR3 (0.51) | TACR3DCAF1CTSAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | TACR3 3996/4885DCAF1 2372/4885CTSA 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.