Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061813 | 0.88 | FTO (0.40) | FTOHPGDMEN1MAPTHTT | |
| SCHEMBL321053 | 0.85 | FTO (0.42) | FTOHPGDMEN1MAPTHTT | |
| SCHEMBL5596736 | 0.76 | FTO (0.69) | FTOHPGDMEN1MAPTHTT | |
| SCHEMBL7048435 | 0.76 | FTO (0.43) | FTOHPGDMEN1MAPTHTT | |
| SCHEMBL917141 | 0.74 | ALB (0.58) | FTOHPGDMEN1MAPTHTT | |
| Fluorescein SCHEMBL3866853 | 0.74 | FTO (0.70) | FTOHPGDMEN1MAPTHTT | |
| Fluorescein SCHEMBL27504008 | 0.74 | FTO (0.82) | FTOHPGDMEN1MAPTHTT | |
| Fluorescein SCHEMBL27395251 | 0.74 | FTO (0.82) | FTOHPGDMEN1MAPTHTT | |
| SCHEMBL4147277 | 0.74 | FTO (0.49) | FTOHPGDMEN1MAPTHTT | |
| Fluorescein SCHEMBL9221862 | 0.73 | FTO (0.77) | FTOHPGDMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120177593-A1 | SYNTHESIS OF DENDRIMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-07-12 | — | — | US | claimed |
| WO-2011011384-A9 | SYNTHESIS OF DENDRIMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-07-21 | — | — | WO | claimed |
| WO-2011011384-A2 | SYNTHESIS OF DENDRIMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-01-27 | — | — | WO | claimed |
| EP-1773936-A4 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | PENN STATE RES FOUND (US) | 2008-10-08 | — | — | EP | claimed |
| EP-1773936-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-04-18 | — | — | EP | claimed |
| US-20050281884-A1 | Unagglomerated core/shell nanocomposite particles | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-22 | — | — | US | claimed |
| WO-2005118702-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-15 | — | — | WO | claimed |
| US-11150358-B2 | Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry | RIKEN (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20200333474-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | RIKEN (JP) | 2020-10-22 | — | — | US | disclosed |
| EP-3686632-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | Riken (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-20170023681-A1 | PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER | NEW YORK UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| EP-1773936-B1 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | PENN STATE RES FOUND (US) | 2015-09-02 | — | — | EP | disclosed |
| US-9086489-B2 | Personal and area self-indicating instant radiation alert dosimeter | JP LABORATORIES, INC (US) | 2015-07-21 | — | — | US | disclosed |
| WO-2005118702-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-1599744-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES, INC. (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2005092326-A1 | SMALL MOLECULE ANTAGONISTS OF XIAP FAMILY PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-10-06 | — | — | WO | disclosed |
| EP-1565216-A1 | NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF | THE UNIVERSITY OF LIVERPOOL (GB) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004077097-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES INC. (US) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004047870-A1 | NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF | THE UNIVERSITY OF LIVERPOOL (GB) | 2004-06-10 | — | — | WO | disclosed |
| WO-2002101012-A2 | REGULATION OF TRANSGENE EXPRESSION FOLLOWING AAV TRANSDUCTION | CHILDREN'S HOSPITAL RESEARCH FOUNDATION (US) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177593-A1 | SYNTHESIS OF DENDRIMER CONJUGATES | TLR3, TLR9, QPCT | FTO 3855/4885HPGD 737/4885MEN1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.