Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321053 | 0.90 | FTO (0.42) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL30366389 | 0.79 | ALB (0.49) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL3201232 | 0.79 | ALB (0.49) | FTOHPGDMEN1MAPTCYP2C19 | |
| Fluorescein SCHEMBL29996358 | 0.77 | FTO (0.52) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL592690 | 0.76 | FTO (0.49) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL15347554 | 0.75 | FTO (0.43) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL22295453 | 0.74 | FTO (0.55) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL29501272 | 0.73 | FTO (0.56) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL164316 | 0.73 | FTO (0.56) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL29995636 | 0.73 | FTO (0.56) | FTOHPGDMEN1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487862-A2 | POLYMER SUPPORTED REAGENTS FOR NATURAL PRODUCTS PURIFICATION | Pharmacia Italia S.p.A. (IT) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078454-A2 | POLYMER SUPPORTED REAGENTS FOR NATURAL PRODUCTS PURIFICATION | PHARMACIA ITALIA SPA (IT) | 2003-09-25 | — | — | WO | disclosed |