Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225059 | 0.99 | RAB9A (0.46) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5225048 | 0.99 | RAB9A (0.46) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5224071 | 0.92 | S1PR1 (0.47) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5220653 | 0.91 | RAB9A (0.46) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5220668 | 0.91 | RAB9A (0.46) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5222060 | 0.91 | KCNH2 (0.45) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5222076 | 0.91 | KCNH2 (0.45) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5225958 | 0.84 | SMN1; SMN2 (0.59) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5228387 | 0.84 | RAB9A (0.51) | KCNH2GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5225149 | 0.83 | SMN1; SMN2 (0.61) | KCNH2RAB9ASMN1; SMN2NPC1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060019998-A1 | Histamine-3 receptor antagonist | PFIZER INC | 2006-01-26 | — | — | US | claimed |
| US-20060019998-A1 | Histamine-3 receptor antagonist | PFIZER INC | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019998-A1 | Histamine-3 receptor antagonist | HRH3, HRH4, HRH2 | KCNH2 909/4885GPR119 34/4885RAB9A 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.