Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928702 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL5928722 | 0.67 | KDM4E (0.49) | MAPTRAB9AKDM4EGAAMEN1 | |
| SCHEMBL5928726 | 0.67 | KDM4E (0.49) | MAPTRAB9AKDM4EGAAMEN1 | |
| SCHEMBL8883561 | 0.66 | LMNA (0.60) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL5928897 | 0.65 | MEN1 (0.63) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL5928895 | 0.65 | MEN1 (0.63) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL5928844 | 0.64 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL5928851 | 0.64 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL8498648 | 0.64 | HTT (0.51) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL26821100 | 0.64 | HTT (0.51) | SMN1; SMN2MAPTRAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | HPGDS, PTGS1, PTGDR | SMN1; SMN2 4744/4885MAPT 4875/4885RAB9A 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.