Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329461 | 0.82 | APP (0.44) | APPKCNH2GRM5GABRA1LMNA | |
| SCHEMBL28282150 | 0.79 | NPC1 (0.50) | APPKCNH2GRM5GABRA1LMNA | |
| SCHEMBL3796509 | 0.74 | APP (0.80) | APPKCNH2GRM5CYP1A2CYP3A4 | |
| SCHEMBL11036599 | 0.72 | GABRA1 (0.52) | GABRA1LMNACYP1A2CYP3A4HPGD | |
| SCHEMBL19455956 | 0.71 | APP (0.57) | APPKCNH2GRM5LMNACYP1A2 | |
| Benzene SCHEMBL3121322 | 0.71 | GABRA1 (0.60) | GABRA1LMNACYP1A2CYP3A4HPGD | |
| Benzene SCHEMBL28101242 | 0.71 | GABRA1 (0.60) | GABRA1LMNACYP1A2CYP3A4HPGD | |
| Diphenylacetylene SCHEMBL960609 | 0.71 | APP (1.00) | APPKCNH2GRM5CYP1A2CYP3A4 | |
| Diphenylacetylene SCHEMBL68254 | 0.71 | APP (1.00) | APPKCNH2GRM5CYP1A2CYP3A4 | |
| Diphenylacetylene SCHEMBL29188592 | 0.71 | APP (1.00) | APPKCNH2GRM5CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263018-B2 | Detecting aggregation-induced emission via fluorescence | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-09-11 | — | — | US | disclosed |
| US-20060240565-A1 | Environment sensor and conjugated polyene for manufacturing environment sensors | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) | 2006-10-26 | — | — | US | disclosed |