Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196593 | 0.89 | KCNH2 (0.37) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL29532555 | 0.89 | KCNH2 (0.37) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL4876105 | 0.88 | KCNH2 (0.35) | KCNH2HRH3 | |
| SCHEMBL5197919 | 0.88 | KCNH2 (0.38) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL5196238 | 0.87 | SCN9A (0.40) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL5218646 | 0.86 | KCNH2 (0.39) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL5221066 | 0.85 | TP53 (0.36) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL5225994 | 0.85 | ALDH1A1 (0.38) | MMP12KCNH2HRH3SCN9APTGER4 | |
| SCHEMBL5223193 | 0.84 | PRKCA (0.37) | PRKCAMMP12KCNH2HRH3SCN9A | |
| SCHEMBL5198484 | 0.83 | KCNH2 (0.37) | KCNH2HRH3SCN9ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211698-A1 | Bicyclic heteroaryl derivatives for treating viruses | GENELABS, INC. | 2006-09-21 | — | — | US | claimed |
| US-20060211698-A1 | Bicyclic heteroaryl derivatives for treating viruses | GENELABS, INC. | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211698-A1 | Bicyclic heteroaryl derivatives for treating viruses | HAVCR2, ZC3HAV1, SARS1 | PRKCA 4500/4885MMP12 4114/4885KCNH2 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.