Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.56 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 9/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083663 | 0.95 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL28780810 | 0.87 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL28170063 | 0.79 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL632264 | 0.79 | ZDHHC20 (0.75) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL1592093 | 0.77 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL269468 | 0.77 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL270209 | 0.77 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL58169 | 0.77 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL8405507 | 0.77 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 | |
| SCHEMBL1591868 | 0.77 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | ZDHHC20 1730/4885ZDHHC2 3218/4885TGM2 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.