Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoglycyrol SCHEMBL29354283 | 1.00 | TP53 (0.58) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL27827659 | 0.78 | TP53 (0.53) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL30637608 | 0.78 | ESR1 (0.54) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL15383648 | 0.72 | ESR1 (0.65) | KMT2AKDM4EALDH1A1GLAGAA | |
| Glycyrol SCHEMBL758197 | 0.69 | ALOX5AP (0.65) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL28008322 | 0.69 | ALOX5AP (0.59) | KMT2AKDM4EALDH1A1GLAGAA | |
| Glycyrol SCHEMBL29499208 | 0.69 | ALOX5AP (0.65) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL30266809 | 0.68 | MAPT (0.76) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL4778019 | 0.68 | MAPT (0.76) | TP53CYP3A4KMT2AKDM4EALDH1A1 | |
| Coumestrol SCHEMBL22012 | 0.68 | ESR2 (1.00) | CYP3A4KMT2AKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060269494-A1 | New Ubiquitin-Proteasome Regulating Compounds and Their Application in Cosmetic and Pharmaceutical Formulations | GUPTA SHYAM K | 2006-11-30 | — | — | US | disclosed |