Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Licopyranocoumarin SCHEMBL2221932 | 0.89 | TYR (0.42) | TP53CYP3A4TYRNUDT1PDE4D | |
| Licopyranocoumarin SCHEMBL29439925 | 0.89 | TYR (0.42) | TP53CYP3A4TYRNUDT1PDE4D | |
| Isoglycyrol SCHEMBL29354283 | 0.78 | TP53 (0.58) | TP53CYP3A4NUDT1PDE4DPDE5A | |
| Isoglycyrol SCHEMBL5935152 | 0.78 | TP53 (0.58) | TP53CYP3A4NUDT1PDE4DPDE5A | |
| Glycycoumarin SCHEMBL759406 | 0.68 | PTPN1 (0.75) | TP53CYP3A4TYRNUDT1PDE4D | |
| Glycyrin SCHEMBL5327472 | 0.68 | PTPN1 (0.75) | TYRPDE4DNFKB1RELAKDM4E | |
| Glycycoumarin SCHEMBL29390258 | 0.68 | PTPN1 (0.75) | TP53CYP3A4TYRNUDT1PDE4D | |
| Glycyrin SCHEMBL29388094 | 0.68 | PTPN1 (0.75) | TYRPDE4DNFKB1RELAKDM4E | |
| SCHEMBL30637608 | 0.67 | ESR1 (0.54) | TP53CYP3A4PDE4DPDE5ALMNA | |
| SCHEMBL11444801 | 0.65 | PDE5A (0.49) | TP53CYP3A4NUDT1PDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106046015-A | Specific probe substrates for CYP450 (cytochrome P450) 2A6 enzyme and application of specific probe substrates | 北京大学 | 2016-10-26 | — | — | CN | claimed |
| CN-115721671-A | Method for extracting and separating effective components of liquorice root in full-industrial-chain cooperation manner | 李玉山 | 2023-03-03 | — | — | CN | disclosed |
| CN-106046015-B | The Specific probe of a kind of Cytochrome P450 2A6 enzymes and its application | 北京大学 | 2018-06-05 | — | — | CN | disclosed |
| CN-106046015-B | The Specific probe of a kind of Cytochrome P450 2A6 enzymes and its application | 北京大学 | 2018-06-05 | — | — | CN | disclosed |
| CN-106046015-A | Specific probe substrates for CYP450 (cytochrome P450) 2A6 enzyme and application of specific probe substrates | 北京大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-106046015-A | Specific probe substrates for CYP450 (cytochrome P450) 2A6 enzyme and application of specific probe substrates | 北京大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-102068537-B | The preparation of Pericarpium Citri Reticulatae Radix Glycyrrhizae prevents and treats the health food of nasopharyngeal carcinoma and the production method of medicine | GUANGDONG MEDICAL COLLEGE (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-104861015-A | Synergistic clean extraction method of effective components in licorice root | LI YUSHAN | 2015-08-26 | — | — | CN | disclosed |
| CN-102068537-A | Production method for preparing health care foods and medicaments for preventing and treating nasopharyngeal darcinoma by using tangerine peel and liquoric root | GUANGDONG MEDICAL COLLEGE | 2011-05-25 | — | — | CN | disclosed |
| CN-101982465-A | Flavonoid compound extracted from liquorice and preparation method and application thereof | NINGXIA INST FOR DRUG CONTROL | 2011-03-02 | — | — | CN | disclosed |