Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 5/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355490 | 0.80 | SSTR4 (0.38) | SSTR4CTSCREN | |
| SCHEMBL7355503 | 0.80 | SSTR4 (0.38) | SSTR4CTSCREN | |
| Hydrochloric Acid SCHEMBL7362075 | 0.79 | SSTR4 (0.37) | SSTR4CTSCREN | |
| Hydrochloric Acid SCHEMBL7362072 | 0.79 | SSTR4 (0.37) | SSTR4CTSCREN | |
| SCHEMBL28716642 | 0.77 | SSTR4 (0.44) | SSTR4CTSCREN | |
| Hydrochloric Acid SCHEMBL7362739 | 0.76 | ALPI (0.45) | SSTR4CTSCRENDPP4 | |
| Hydrochloric Acid SCHEMBL7362750 | 0.76 | ALPI (0.45) | SSTR4CTSCRENDPP4 | |
| SCHEMBL25015428 | 0.73 | SSTR4 (0.44) | SSTR4CTSCREN | |
| SCHEMBL12418702 | 0.73 | SSTR4 (0.44) | SSTR4CTSCREN | |
| SCHEMBL9852723 | 0.72 | SSTR4 (0.44) | SSTR4CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166985-A1 | Pyrrolydin-2-one derivatives as inhibitors of thrombin and factor xa | GLAXO GROUP LIMITED (GB) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166985-A1 | Pyrrolydin-2-one derivatives as inhibitors of thrombin and factor xa | TFPI, TFPI2, SERPINC1 | SSTR4 4595/4885CTSC 137/4885REN 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.