SCHEMBL12418702

SCHEMBL12418702

CC(C)C(=O)C1CNCCO1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 10/20 0.44
REN P00797 9/20 0.41
CTSC P53634 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25015428 1.00 SSTR4 (0.44) SSTR4RENCTSC
SCHEMBL7315375 0.87 SSTR4 (0.45) SSTR4RENCTSC
SCHEMBL28716642 0.85 SSTR4 (0.44) SSTR4RENCTSC
SCHEMBL28740378 0.82 REN (0.43) SSTR4REN
SCHEMBL294493 0.81 SSTR4 (0.40) SSTR4RENCTSC
SCHEMBL29013122 0.81 SSTR4 (0.37) SSTR4REN
SCHEMBL29018289 0.80 SSTR4 (0.41) SSTR4REN
SCHEMBL7355490 0.79 SSTR4 (0.38) SSTR4RENCTSC
SCHEMBL7355503 0.79 SSTR4 (0.38) SSTR4RENCTSC
SCHEMBL37447 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861752-A Photosensitive ink 惠州市兴顺和电子有限公司 2021-12-31 CN claimed
CN-110023307-B Oxime ester compound and photopolymerization initiator containing the same 株式会社艾迪科 2024-01-02 CN disclosed
CN-110248949-B Immunoproteasome inhibitors 普林斯匹亚生物制药公司 2023-02-17 CN disclosed
US-11318205-B1 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2022-05-03 US disclosed
EP-3728218-B1 AMINO INDOLE COMPOUNDS USEFUL AS TLR INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2021-12-01 EP disclosed
US-10874743-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2020-12-29 US disclosed
US-20200339581-A1 AMINO INDOLE COMPOUNDS USEFUL AS TLR INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2020-10-29 US disclosed
CN-107473969-B Method for manufacturing substrate having liquid crystal alignment film for horizontal electric field drive type liquid crystal display element 日产化学工业株式会社 2020-10-16 CN disclosed
US-20190192668-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2019-06-27 US disclosed
US-20190076539-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Theraprutics, Inc. (US) 2019-03-14 US disclosed
US-20180057505-A1 BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY VERTEX PHARMACEUTICALS INCORPORATED 2018-03-01 US disclosed
US-20180057505-A1 BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY VERTEX PHARMACEUTICALS INCORPORATED 2018-03-01 US disclosed
US-20110171172-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY MERCK SHARP & DOHME CORP. 2011-07-14 US disclosed
US-20110171172-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY MERCK SHARP & DOHME CORP. 2011-07-14 US disclosed
US-20110150757-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY MERCK SHARP & DOHME CORP. 2011-06-23 US disclosed
US-20110150757-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY MERCK SHARP & DOHME CORP. 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874743-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 SSTR4 4498/4885REN 3694/4885CTSC 491/4885
US-20110150757-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY KIF18B, KIF5B, KIF18A SSTR4 4782/4885REN 3133/4885CTSC 2902/4885
US-20180057505-A1 BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY F2RL1, PARP12, TFPI2 SSTR4 4570/4885REN 1629/4885CTSC 324/4885
US-20190076539-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION GCGR, STUB1, GID4 SSTR4 185/4885REN 2404/4885CTSC 1317/4885
US-20110171172-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY KIF5B, KIF2C, KIFC1 SSTR4 4726/4885REN 3330/4885CTSC 3082/4885
US-20190192668-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 SSTR4 4498/4885REN 3694/4885CTSC 491/4885
US-20200339581-A1 AMINO INDOLE COMPOUNDS USEFUL AS TLR INHIBITORS TLR7, TLR1, TLR9 SSTR4 934/4885REN 1840/4885CTSC 1893/4885
US-11318205-B1 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 SSTR4 4498/4885REN 3694/4885CTSC 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.