Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936602 | 0.88 | HDAC1 (0.48) | MAPTTP53RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL5936600 | 0.84 | CACNA1H (0.70) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1122672 | 0.79 | PKM (0.63) | MAPTHDAC1MEN1KMT2AHDAC6 | |
| SCHEMBL1123361 | 0.77 | MAPT (0.67) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1123437 | 0.75 | PTPN1 (0.67) | RAB9A | |
| SCHEMBL5936665 | 0.74 | CACNA1H (0.56) | MAPTSMN1; SMN2CACNA1HCACNA1BHDAC1 | |
| SCHEMBL21798722 | 0.74 | NPC1 (0.64) | TP53NPC1RAB9AHDAC1LMNA | |
| SCHEMBL29894079 | 0.74 | NPC1 (0.64) | TP53NPC1RAB9AHDAC1LMNA | |
| SCHEMBL6351462 | 0.73 | AKR1C2 (0.58) | MAPTTP53RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL29937768 | 0.73 | PSMB1 (0.60) | HDAC1ALDH1A1MCHR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | MAPT 4365/4885TP53 1778/4885RXFP1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.