SCHEMBL593755

SCHEMBL593755

Cc1cc(C)c(CN2CCNCC2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
CXCR4 P61073 3/20 0.46
HRH3 Q9Y5N1 2/20 0.46
SIGMAR1 Q99720 1/20 0.44
EPHX2 P34913 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
ADRA2C P18825 1/20 0.41
CCR2 P41597 1/20 0.41
CXCL12 P48061 1/20 0.41
BLM P54132 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PDE10A Q9Y233 1/20 0.40
CFB P00751 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2008758 0.93 CXCR4 (0.56) LMNACXCR4HRH3SIGMAR1EPHX2
SCHEMBL10425103 0.84 LMNA (0.46) LMNACXCR4HRH3SIGMAR1MEN1
SCHEMBL8667328 0.81 HRH3 (0.71) LMNACXCR4HRH3SIGMAR1MEN1
SCHEMBL917995 0.81 LMNA (0.64) LMNACXCR4HRH3SIGMAR1MEN1
SCHEMBL10465208 0.79 LMNA (0.42) LMNACXCR4HRH3SIGMAR1MEN1
SCHEMBL26121408 0.78 HRH3 (0.47) HRH3EPHX2MEN1KMT2ACFB
SCHEMBL3971878 0.78 CXCR4 (0.56) LMNACXCR4HRH3SIGMAR1MEN1
SCHEMBL11891933 0.78 HRH3 (0.52) LMNAHRH3EPHX2ALDH1A1
SCHEMBL10701848 0.77 HRH3 (0.46) LMNAHRH3EPHX2MEN1KMT2A
SCHEMBL2097149 0.77 HRH3 (0.46) HRH3EPHX2MEN1KMT2ACFB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
CN-118834313-A Zwitterionic polymer, ion exchange membrane, and preparation methods and applications thereof 佛山绿动氢能科技有限公司 2024-10-25 CN disclosed
CN-117487047-A Phosphonic acid functionalized polymer, multifunctional styrene polymer and application thereof 国家电投集团氢能科技发展有限公司 2024-02-02 CN disclosed
CN-117362485-A Hydroxymethyl functionalized vinyl polymers, multifunctional polymers and uses thereof 国家电投集团氢能科技发展有限公司 2024-01-09 CN disclosed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN disclosed
US-20160009903-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORPORATION (JP) 2016-01-14 US disclosed
US-20160009903-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORPORATION (JP) 2016-01-14 US disclosed
EP-2257591-B1 FUNCTIONALIZED POLYMERS AND INITIATORS FOR MAKING SAME BRIDGESTONE CORP (JP) 2014-12-17 EP disclosed
US-20140357784-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME JSR CORPORATION (JP) 2014-12-04 US disclosed
EP-0314041-A1 New rifamycin derivatives CIBA-GEIGY AG (CH) 1989-05-03 EP disclosed
WO-1989002894-A1 DIACYL DERIVATIVES OF 4-(TRIALKYLBENZYL)-PIPERAZINYL COMPOUNDS CIBA-GEIGY AG (CH) 1989-04-06 WO disclosed
EP-0308568-A1 Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed
EP-0284552-A1 4-Benzyl-piperazinyl-hydrazones CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed
EP-0244398-A1 SUBSTITUTED 4-BENZYL-PIPERAZINYL COMPOUNDS. CIBA GEIGY AG (CH) 1987-11-11 EP disclosed
WO-1987002361-A1 SUBSTITUTED 4-BENZYL-PIPERAZINYL COMPOUNDS CIBA-GEIGY AG (CH) 1987-04-23 WO disclosed
US-4374990-A ANTIDEPRESSANTS HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-22 US disclosed
US-4115569-A PARASITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed