Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941232 | 0.91 | TP53 (0.47) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5079875 | 0.87 | TSHR (0.53) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5082861 | 0.87 | LMNA (0.47) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5079977 | 0.87 | LMNA (0.47) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5079972 | 0.87 | PDCD1 (0.49) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5082882 | 0.84 | ALDH1A1 (0.45) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL14690431 | 0.84 | LMNA (0.50) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL570134 | 0.84 | LMNA (0.50) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL443825 | 0.83 | ALDH1A1 (0.54) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5941243 | 0.83 | TSHR (0.49) | TSHRTP53LMNAPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287446-A1 | Catalyst component for olefin polymerization and catalyst comprising the same | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) | 2006-12-21 | — | — | US | disclosed |