Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082847 | 0.86 | TSHR (0.47) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5082833 | 0.86 | PDCD1 (0.50) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5079875 | 0.85 | TSHR (0.53) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5082891 | 0.85 | MEN1 (0.47) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5079860 | 0.85 | TSHR (0.47) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL571292 | 0.85 | TSHR (0.52) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5941280 | 0.83 | TSHR (0.47) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5941353 | 0.83 | TSHR (0.50) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5941367 | 0.83 | TSHR (0.50) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL4837043 | 0.82 | TSHR (0.49) | TSHRTP53PDCD1CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287446-A1 | Catalyst component for olefin polymerization and catalyst comprising the same | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) | 2006-12-21 | — | — | US | disclosed |