Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082867 | 0.87 | KMT2A (0.61) | TSHRTP53CYP2D6KMT2ASLC6A2 | |
| SCHEMBL5083408 | 0.87 | PDCD1 (0.49) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5082842 | 0.85 | MMP8 (0.48) | TSHRTP53PDCD1CD274KMT2A | |
| SCHEMBL5082172 | 0.84 | KMT2A (0.46) | TSHRTP53CYP2D6PDCD1CD274 | |
| SCHEMBL5079875 | 0.84 | TSHR (0.53) | TSHRTP53CYP2D6PDCD1CD274 | |
| SCHEMBL5941374 | 0.83 | TSHR (0.51) | TSHRTP53CYP2D6PDCD1CD274 | |
| SCHEMBL5941251 | 0.82 | SLC1A3 (0.47) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16366772 | 0.82 | CYP2D6 (0.54) | TSHRTP53CYP2D6PDCD1CD274 | |
| SCHEMBL6568637 | 0.82 | CYP2D6 (0.54) | TSHRTP53CYP2D6PDCD1CD274 | |
| SCHEMBL5941367 | 0.81 | TSHR (0.50) | TSHRTP53CYP2D6PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287446-A1 | Catalyst component for olefin polymerization and catalyst comprising the same | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) | 2006-12-21 | — | — | US | disclosed |