Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 8/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24092000 | 0.86 | MCHR1 (0.57) | MCHR1NPC1RAB9ADDB1CRBN | |
| SCHEMBL29911218 | 0.86 | MCHR1 (0.57) | MCHR1NPC1RAB9ADDB1CRBN | |
| SCHEMBL16666168 | 0.83 | NPC1 (0.56) | MCHR1NPC1RAB9ADDB1CRBN | |
| SCHEMBL6456504 | 0.82 | NCF1 (0.49) | MCHR1PIM1PIM2NPC1RAB9A | |
| SCHEMBL5943499 | 0.82 | NCF1 (0.49) | MCHR1PIM1PIM2NPC1RAB9A | |
| SCHEMBL9056686 | 0.82 | NPC1 (0.59) | MCHR1NPC1RAB9ADDB1CRBN | |
| SCHEMBL5431722 | 0.81 | MCHR1 (0.59) | MCHR1PIM1PIM2CXCR3 | |
| Hydrochloric Acid SCHEMBL6924108 | 0.81 | NCF1 (0.47) | MCHR1PIM1PIM2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6463442 | 0.81 | NCF1 (0.47) | MCHR1PIM1PIM2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8852766 | 0.80 | NPC1 (0.57) | MCHR1NPC1RAB9ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | MCHR1, HCRTR1, MC3R | MCHR1 1/4885PIM1 2565/4885PIM2 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.