Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978299 | 0.85 | MCHR1 (0.62) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| SCHEMBL7978296 | 0.85 | MCHR1 (0.62) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| SCHEMBL5780729 | 0.85 | MCHR1 (0.62) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| SCHEMBL7978307 | 0.85 | MCHR1 (0.62) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| SCHEMBL6459301 | 0.85 | KDM4E (0.75) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| SCHEMBL6456703 | 0.85 | KDM4E (0.75) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL6928682 | 0.84 | KDM4E (0.73) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL6461411 | 0.84 | KDM4E (0.73) | KDM4ESMN1; SMN2LMNAMCHR1MEN1 | |
| SCHEMBL5433640 | 0.84 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2LMNAMCHR1ALDH1A1 | |
| SCHEMBL5943481 | 0.82 | MCHR1 (0.62) | KDM4ESMN1; SMN2LMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | MCHR1, HCRTR1, MC3R | KDM4E 1505/4885SMN1; SMN2 621/4885LMNA 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.