Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799103 | 0.94 | MCHR1 (0.62) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5433478 | 0.94 | MCHR1 (0.62) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5440300 | 0.91 | MCHR1 (0.64) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5433454 | 0.85 | MCHR1 (0.60) | MCHR1 | |
| SCHEMBL5433640 | 0.84 | ALDH1A1 (0.56) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5943477 | 0.82 | KDM4E (0.74) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5434552 | 0.81 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL7978299 | 0.78 | MCHR1 (0.62) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7978307 | 0.78 | MCHR1 (0.62) | MCHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7978296 | 0.78 | MCHR1 (0.62) | MCHR1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | US | disclosed |
| EP-1528924-A1 | MCH1R ANTAGONISTS | Astrazeneca AB (SE) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004004726-A1 | MCHIR ANTAGONISTS | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | MCHR1, HCRTR1, MC3R | MCHR1 1/4885KDM4E 1505/4885LMNA 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.