Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 5/20 | 0.56 |
| ▸ | MC5R | P33032 | 4/20 | 0.53 |
| ▸ | MC3R | P41968 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619967 | 0.81 | MC1R (0.50) | MC1RMC5RMC3RBCHEACHE | |
| SCHEMBL5943511 | 0.77 | CA1 (0.42) | NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5943486 | 0.76 | NCF1 (0.59) | KMT2APOLBNPC1TP53RAB9A | |
| SCHEMBL5943504 | 0.76 | NPC1 (0.51) | KMT2ANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5943461 | 0.76 | NPC1 (0.43) | KMT2ANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5943519 | 0.75 | MCHR1 (0.59) | MC1RBCHEACHEKMT2AMEN1 | |
| SCHEMBL6618405 | 0.73 | KMT2A (0.37) | BCHEACHEKMT2AMEN1POLB | |
| SCHEMBL9308731 | 0.73 | MC1R (0.73) | MC1RMC5RMC3RBCHEACHE | |
| SCHEMBL5943554 | 0.73 | MC5R (0.57) | MC1RMC5RMC3RBCHEACHE | |
| SCHEMBL1520322 | 0.72 | MC1R (0.88) | MC1RMC5RMC3RKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247439-A1 | Mchir antagonists | MCHR1, HCRTR1, MC3R | MC1R 18/4885MC5R 12/4885MC3R 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.