SCHEMBL5943583

SCHEMBL5943583

Oc1ccc(O)c2nc(Cc3ccc4c(O)ccc(O)c4n3)ccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 0.42
KMT2A Q03164 1/20 0.42
CCR1 P32246 2/20 0.37
PDE10A Q9Y233 7/20 0.36
CTSB P07858 2/20 0.35
CTSH P09668 1/20 0.35
KDM4A O75164 2/20 0.33
IDO1 P14902 1/20 0.33
PDE4D Q08499 1/20 0.33
BRD4 O60885 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL325434 0.98 OPRK1 (0.41) OPRK1KMT2ACCR1PDE10ACTSB
SCHEMBL11277502 0.85 CCR1 (0.56) OPRK1KMT2ACCR1PDE10ACTSB
SCHEMBL4395732 0.84 MAPT (0.49) OPRK1KMT2ACCR1PDE10ACTSB
SCHEMBL12834067 0.74 KDM4E (0.40) OPRK1KMT2ABRD4KDM4ENPC1
SCHEMBL3212638 0.72 METAP2 (0.57) KMT2ACCR1PDE10APDE4DKDM4E
SCHEMBL4393540 0.72 MAPT (0.49) OPRK1KMT2ACCR1PDE10ACTSB
SCHEMBL11358186 0.71 KMT2A (0.44) OPRK1KMT2ACTSBCTSHKDM4A
SCHEMBL3275602 0.71 KMT2A (0.77) OPRK1KMT2ACCR1CTSBCTSH
SCHEMBL14293090 0.70 CCR1 (0.47) OPRK1KMT2ACCR1PDE10ACTSB
SCHEMBL7171554 0.70 KMT2A (0.74) OPRK1KMT2ACCR1CTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060214553-A1 Organic electroluminescent device KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2006-09-28 US disclosed
EP-1613132-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kabushiki Kaisha Toyota Jidoshokki (JP) 2006-01-04 EP disclosed
US-6809473-B2 Organic electro-luminescence display element, finder screen display device, finder and optical device MINOLTA CO., LTD. (JP) 2004-10-26 US disclosed
US-20020127431-A1 Organic electro-luminescence display element, finder screen display device, finder and optical device Konica Minolta, Inc. (JP) 2002-09-12 US disclosed