Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945040 | 0.86 | ALDH1A1 (0.35) | TLR8ALDH1A1 | |
| SCHEMBL5944760 | 0.76 | — | — | |
| SCHEMBL5944667 | 0.76 | CHEK1 (0.39) | TLR8ALDH1A1 | |
| SCHEMBL5944719 | 0.71 | KMT2A (0.38) | — | |
| SCHEMBL7150417 | 0.70 | TP53 (0.41) | CRHR1ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL2896836 | 0.70 | DRD3 (0.38) | CRHR1ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL5944865 | 0.69 | HTR1A (0.38) | — | |
| SCHEMBL10620529 | 0.66 | ESR1 (0.47) | CRHR1ALDH3A1ALDH1A3ALDH1A1ESR1 | |
| SCHEMBL11314107 | 0.65 | — | — | |
| SCHEMBL23349106 | 0.65 | TSHR (0.39) | CRHR1ALDH3A1ALDH1A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156481-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156481-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156481-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KRTCAP2, NOX5 | CRHR1 4814/4885TLR8 4224/4885ALDH3A1 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.