⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891549 | 1.00 | — | — | |
| SCHEMBL8892185 | 0.87 | HTR2A (0.47) | — | |
| SCHEMBL8891926 | 0.78 | MEN1 (0.54) | — | |
| SCHEMBL8893548 | 0.78 | HTR2A (0.47) | — | |
| SCHEMBL8890510 | 0.72 | — | — | |
| SCHEMBL9280508 | 0.70 | HTR2A (0.59) | — | |
| SCHEMBL9280516 | 0.70 | HTR2A (0.59) | — | |
| SCHEMBL2048897 | 0.69 | HTR2A (0.53) | — | |
| SCHEMBL9309477 | 0.69 | DRD2 (0.68) | — | |
| SCHEMBL9307961 | 0.69 | DRD2 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114574505-B | Mono-oxygenase gene phzO, coded protein, genetic engineering strain, construction method and application thereof | 上海交通大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-114574505-A | Monooxygenase gene phzO, encoded protein, genetic engineering strain, construction method and application thereof | 上海交通大学 | 2022-06-03 | — | — | CN | disclosed |
| US-20060217394-A1 | Treatment of anhedonia | SILVAN S. TOMKINS INSTITUTE, INC. | 2006-09-28 | — | — | US | disclosed |