SCHEMBL59477

SCHEMBL59477

Nc1cccc(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31167436 1.00
Hydrochloric Acid SCHEMBL22263487 0.97 CYP3A4 (0.41)
Sulfuric Acid SCHEMBL8667555 0.86 CES2 (0.43)
SCHEMBL928091 0.84
SCHEMBL28946305 0.82 TAAR1 (0.42)
Trifluoroacetic Acid SCHEMBL3596920 0.81 CES1 (0.44)
SCHEMBL3644248 0.78 ALDH1A1 (0.46)
SCHEMBL398474 0.78 ALDH1A1 (0.59)
SCHEMBL180426 0.77
SCHEMBL8166926 0.77 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2416 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-119674089-A Composite current collector and preparation method and application thereof 江苏正力新能电池技术股份有限公司 2025-03-21 CN claimed
CN-119432288-A Adhesive composition and preparation method and application thereof 江苏正力新能电池技术股份有限公司 2025-02-14 CN claimed
CN-119384196-A Method for improving perovskite solar cell performance by using fluoroaniline/difluoroaniline molecules and application of method 云南大学 2025-01-28 CN claimed
CN-118183708-A Method for preparing fluorocarbon material by using fluorine-containing polymer 重庆大学锂电及新材料遂宁研究院 2024-06-14 CN claimed
CN-117654560-B Method for continuously preparing nitro compound by oxidizing amino 安徽泽升科技股份有限公司 2024-06-04 CN claimed
CN-118085884-A Isothiocyanate liquid crystal compound containing 2, 3-difluoro-substituted benzene and liquid crystal composition 西安近代化学研究所 2024-05-28 CN claimed
CN-117427568-B Catalytic hydrogenation system for preparing 2,4 difluoroaniline 池州飞昊达化工有限公司 2024-04-16 CN claimed
CN-117654560-A Method for continuously preparing nitro compound by oxidizing amino 安徽泽升科技股份有限公司 2024-03-08 CN claimed
CN-117427568-A Catalytic hydrogenation system for preparing 2,4 difluoroaniline 池州飞昊达化工有限公司 2024-01-23 CN claimed
CN-1048012-C Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole DOWELANCO (US) 2000-01-05 CN claimed
EP-0667337-B1 Method for preparing fluoroanilines CLARIANT GMBH (DE) 1998-01-21 EP claimed
US-5498794-A Process for preparing fluoroanilines HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-12 US claimed
EP-0667337-A1 Method for preparing fluoroanilines HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-16 EP claimed
CN-1100722-A Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole DOWELANCO (US) 1995-03-29 CN claimed
EP-0427336-B1 Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole DOWELANCO (US) 1995-02-01 EP claimed
CN-1051557-A Process for preparing 5-amino-3-chlorosulfonyl-1, 2, 4-triazole DOWELANCO (US) 1991-05-22 CN claimed
EP-0427336-A1 Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole DOWELANCO (US) 1991-05-15 EP claimed
US-5008396-A Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole DOWELANCO (US) 1991-04-16 US claimed
US-4343951-A Method for the preparation of fluoroaniline HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-08-10 US claimed