Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572868 | 1.00 | GRM4 (0.32) | GRM4EPHX1HIF1AALDH1A1HSD17B10 | |
| SCHEMBL819984 | 1.00 | GRM4 (0.32) | GRM4EPHX1HIF1AALDH1A1HSD17B10 | |
| SCHEMBL20489359 | 1.00 | GRM4 (0.32) | GRM4EPHX1HIF1AALDH1A1HSD17B10 | |
| SCHEMBL11572873 | 1.00 | GRM4 (0.32) | GRM4EPHX1HIF1AALDH1A1HSD17B10 | |
| SCHEMBL11572951 | 1.00 | GRM4 (0.32) | GRM4EPHX1HIF1AALDH1A1HSD17B10 | |
| SCHEMBL13557475 | 0.96 | GRM4 (0.33) | GRM4ALDH1A1 | |
| SCHEMBL11568758 | 0.96 | GRM4 (0.33) | GRM4ALDH1A1 | |
| SCHEMBL91320 | 0.96 | GRM4 (0.33) | GRM4ALDH1A1 | |
| SCHEMBL29652344 | 0.96 | GRM4 (0.33) | GRM4ALDH1A1 | |
| SCHEMBL819809 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382241-B1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORP (JP) | 2016-11-23 | — | — | EP | claimed |
| US-8785566-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2014-07-22 | — | — | US | claimed |
| US-5874625-A | Process to hydrogenate organic nitriles to primary amines | HENKEL CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| WO-1998019991-A1 | IMPROVED PROCESS TO HYDROGENATE ORGANIC NITRILES TO PRIMARY AMINES | HENKEL CORPORATION (US) | 1998-05-14 | — | — | WO | claimed |
| US-5145594-A | Consisting of mono- or dinitriles, aliphatic, cyclic or tricycic | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| US-4146552-A | Dehydrogenation of cis-1,2-dicyanocycloalkane | PHILLIPS PETROLEUM COMPANY (US) | 1979-03-27 | — | — | US | claimed |
| CN-111936461-B | Process for producing dicyanoalkane and bis (aminomethyl) alkane | 三菱瓦斯化学株式会社 | 2023-09-05 | — | — | CN | disclosed |
| US-11542222-B2 | Method for preparing dicyanoalkane and bis(aminomethyl) alkane | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-01-03 | — | — | US | disclosed |
| US-20210139408-A1 | METHOD FOR PREPARING DICYANOALKANE AND BIS(AMINOMETHYL)ALKANE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-05-13 | — | — | US | disclosed |
| EP-3778559-A1 | METHOD FOR PREPARING DICYANOALKANE AND BIS(AMINOMETHYL)ALKANE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-02-17 | — | — | EP | disclosed |
| CN-111936461-A | Process for producing dicyanoalkane and bis (aminomethyl) alkane | 三菱瓦斯化学株式会社 | 2020-11-13 | — | — | CN | disclosed |
| WO-2019198782-A1 | METHOD FOR PREPARING DICYANOALKANE AND BIS(AMINOMETHYL)ALKANE | 三菱瓦斯化学株式会社 | 2019-10-17 | — | — | WO | disclosed |
| US-10081688-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2018-09-25 | — | — | US | disclosed |
| WO-2010085631-A2 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |
| WO-2007001848-A2 | HIGH REFRACTIVE INDEX FLUIDS WITH LOW ABSORPTION FOR IMMERSION LITHOGRAPHY | SACHEM, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-5874625-A | Process to hydrogenate organic nitriles to primary amines | HENKEL CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1998019991-A1 | IMPROVED PROCESS TO HYDROGENATE ORGANIC NITRILES TO PRIMARY AMINES | HENKEL CORPORATION (US) | 1998-05-14 | — | — | WO | disclosed |
| US-5145594-A | Consisting of mono- or dinitriles, aliphatic, cyclic or tricycic | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4885391-A | HYDROGENATION OF 2-METHYLGLUTARONITRILE WITH CHROMIUM PROMOTED COBALT RANEY CATALYST ACTIVATED BY WATER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| US-4146552-A | Dehydrogenation of cis-1,2-dicyanocycloalkane | PHILLIPS PETROLEUM COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139408-A1 | METHOD FOR PREPARING DICYANOALKANE AND BIS(AMINOMETHYL)ALKANE | AADAT, DDC, ALB | GRM4 3662/4885EPHX1 4825/4885HIF1A 2323/4885 |
| US-11542222-B2 | Method for preparing dicyanoalkane and bis(aminomethyl) alkane | AADAT, DDC, ALB | GRM4 3662/4885EPHX1 4825/4885HIF1A 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.