SCHEMBL5950352

SCHEMBL5950352

CCC[Si](CCC)(OC(C)CC)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.31
ABCB1 P08183 1/20 0.31
ABCC1 P33527 1/20 0.31
TRPA1 O75762 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31
GABRE P78334 1/20 0.31
GABRA6 Q16445 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703699 0.87 TSHR (0.31) SIGMAR1
SCHEMBL4278121 0.87 KDM4E (0.35) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL4266076 0.84 MCHR1 (0.33) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL4275381 0.82 MAPT (0.35) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL427067 0.79 MAPT (0.35) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL645558 0.79 ALDH1A1 (0.35) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL4274025 0.77 ABCB1 (0.35) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL4276271 0.77 ESR1 (0.36) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL4266063 0.77 ABCB1 (0.35) KDM4ENPSR1MAPTLMNAABCB1
SCHEMBL703005 0.76 LTA4H (0.34) KDM4ENPSR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060269724-A1 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-11-30 US disclosed
CN-1809764-A Antireflective film ASAHI CHEMICAL IND (JP) 2006-07-26 CN disclosed
US-20040077757-A1 Coating composition for use in producing an insulating thin film ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-04-22 US disclosed