SCHEMBL5950693

SCHEMBL5950693

CC(C)(O)c1ccc(C(C)(C)O)c(Br)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.40
ALOX15 P16050 3/20 0.40
HPGD P15428 3/20 0.40
TSHR P16473 3/20 0.40
HIF1A Q16665 3/20 0.40
ALOX12 P18054 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP3A4 P08684 2/20 0.40
CASP1 P29466 1/20 0.40
RECQL P46063 1/20 0.40
CHEK1 O14757 1/20 0.34
DAPK3 O43293 1/20 0.34
RET P07949 1/20 0.34
PDGFRB P09619 1/20 0.34
PIM1 P11309 1/20 0.34
PDGFRA P16234 1/20 0.34
KDR P35968 1/20 0.34
MAPK8 P45983 1/20 0.34
RPS6KA3 P51812 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732695 0.83 ALOX15 (0.36) HSD17B10ALOX15HPGDTSHRHIF1A
SCHEMBL9274255 0.83 ALOX15 (0.36) HSD17B10ALOX15HPGDTSHRHIF1A
SCHEMBL30573057 0.80 CHRNA1 (0.41) HSD17B10ALOX15HPGDTSHRHIF1A
SCHEMBL137338 0.80 CHRNA1 (0.41) HSD17B10ALOX15HPGDTSHRHIF1A
SCHEMBL548369 0.79 MEN1 (0.36) HSD17B10ALOX15HPGDTSHRALDH1A1
SCHEMBL14958302 0.78 PTPN1 (0.39) HPGDALDH1A1TDP1MEN1KMT2A
SCHEMBL30812285 0.78 ALOX15 (0.63) HSD17B10ALOX15HPGDTSHRHIF1A
SCHEMBL2585723 0.78 HPGD (0.40) HSD17B10ALOX15HPGDTSHRHIF1A
SCHEMBL30623436 0.78 PTPN1 (0.39) HPGDALDH1A1TDP1MEN1KMT2A
SCHEMBL9272585 0.77 ESR1 (0.41) HSD17B10ALOX15HPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159695-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2023-05-25 US disclosed
WO-2023089976-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED OBJECT DIC株式会社 2023-05-25 WO disclosed
WO-2023008079-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT DIC株式会社 2023-02-02 WO disclosed
EP-2782449-B1 ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES ANACOR PHARMACEUTICALS INC (US) 2016-08-03 EP disclosed
EP-2782449-A1 ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES Anacor Pharmaceuticals, Inc. (US) 2014-10-01 EP disclosed
US-8546357-B2 Boron-containing small molecules for controlling ectoparasites ELI LILLY AND COMPANY (US) 2013-10-01 US disclosed
WO-2013078071-A1 ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES ELI LILLY AND COMPANY (US) 2013-05-30 WO disclosed
US-20130131017-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-05-23 US disclosed
US-7005216-B2 Photo mask RENESAS TECHNOLOGY CORP. (JP) 2006-02-28 US disclosed
US-6790564-B2 FOR USE IN PRODUCING SEMICONDUCTOR INTEGRATED CIRCUIT DEVICES; EFFICIENCY RENESAS TECHNOLOGY CORPORATION (JP) 2004-09-14 US disclosed
US-20030129505-A1 Krypton fluoride laser lithography; photoresist pattern RENESAS ELECTRONICS CORPORATION (JP) 2003-07-10 US disclosed
US-20020086222-A1 Photomask and manufacturing method of an electronic device therewith RENESAS ELECTRONICS CORPORATION (JP) 2002-07-04 US disclosed
US-5399715-A Polyamino oligomers and polymaleimide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-21 US disclosed
EP-0577836-A1 POLYAMINO-OLIGOMER AND POLYMALEIMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131017-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BCL6, RB1 HSD17B10 2443/4885ALOX15 4373/4885HPGD 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.