SCHEMBL9274255

SCHEMBL9274255

CC(C)(O)c1ccc(Br)c(C(C)(C)O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.36
ALOX12 P18054 2/20 0.36
HSD17B10 Q99714 4/20 0.35
HPGD P15428 3/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 2/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
JAK2 O60674 1/20 0.33
BTK Q06187 1/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
XBP1 P17861 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732695 1.00 ALOX15 (0.36) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL14726948 0.89 ALDH1A1 (0.43) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL31618336 0.86 MAPT (0.43) ALOX15HSD17B10TSHRCYP3A4MAPT
SCHEMBL5950693 0.83 HSD17B10 (0.40) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL137338 0.80 CHRNA1 (0.41) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL30573057 0.80 CHRNA1 (0.41) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL548369 0.79 MEN1 (0.36) ALOX15HSD17B10HPGDTSHRALDH1A1
SCHEMBL31303011 0.78 ALOX15 (0.45) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL14726956 0.78 SMN1; SMN2 (0.40) ALOX15ALOX12HSD17B10HPGDTSHR
SCHEMBL6931883 0.77 MEN1 (0.34) ALOX15HSD17B10HPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023089976-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED OBJECT DIC株式会社 2023-05-25 WO disclosed
US-20230159695-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2023-05-25 US disclosed
WO-2023008079-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT DIC株式会社 2023-02-02 WO disclosed
US-5399715-A Polyamino oligomers and polymaleimide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-21 US disclosed
EP-0577836-A1 POLYAMINO-OLIGOMER AND POLYMALEIMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-01-12 EP disclosed