Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848745 | 0.86 | ADORA1 (0.52) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13848718 | 0.80 | ADORA1 (0.59) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3342911 | 0.78 | ADORA1 (0.59) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6106928 | 0.75 | ADORA1 (0.88) | ADORA1ADORA2B | |
| SCHEMBL3548181 | 0.75 | ADORA1 (0.62) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4024284 | 0.75 | ADORA1 (0.58) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4191367 | 0.75 | ADORA1 (0.51) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5951710 | 0.74 | ADORA1 (0.58) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3546986 | 0.74 | ADORA1 (0.58) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6104540 | 0.74 | ADORA1 (0.65) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129255-B2 | Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor | BAYER AKTIENGESELLSCHAFT (DE) | 2006-10-31 | — | — | US | disclosed |
| US-20040110946-A1 | Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110946-A1 | Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor | ADORA3, ADORA1, ADORA2A | ADORA1 2/4885ADORA2A 3/4885ALDH1A1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.