Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363466 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EDDB1CRBNGSK3B | |
| SCHEMBL14862969 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EDDB1CRBNGSK3B | |
| SCHEMBL29620035 | 0.76 | DDB1 (0.36) | ALDH1A1KDM4EDDB1CRBNGSK3B | |
| SCHEMBL30459575 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4EDDB1CRBNGSK3B | |
| SCHEMBL1481510 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL29742299 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL29743227 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL60671 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL29743225 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL2056505 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EDDB1CRBNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | ALDH1A1 2415/4885KDM4E 965/4885DDB1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.