SCHEMBL5951485

SCHEMBL5951485

FC(F)(F)C(F)(F)C(F)(F)CCc1ccnc(-c2cc(CCC(F)(F)C(F)(F)C(F)(F)F)ccn2)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 4/20 0.35
LOX P28300 1/20 0.34
NR3C2 P08235 2/20 0.31
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18469878 0.75 NR3C2 (0.38) LOXL2NR3C2
SCHEMBL5326251 0.75 LOXL2 (0.37) LOXL2LOXNR3C2CCR1CCR5
SCHEMBL24637757 0.71 CYP1A2 (0.39) LOXL2LOXNR3C2
SCHEMBL106014 0.70 LOXL2 (0.33) LOXL2LOXNR3C2
SCHEMBL6579639 0.68 KDM4E (0.33) CCR1CCR5CCR8
SCHEMBL16749598 0.67 LOXL2 (0.48) LOXL2CCR1CCR5CCR8
SCHEMBL12826953 0.67 CCR1 (0.44) LOXL2LOXCCR1CCR5CCR8
SCHEMBL30309267 0.67 LOXL2 (0.48) LOXL2CCR1CCR5CCR8
SCHEMBL9340660 0.67 TAAR1 (0.43)
SCHEMBL9341098 0.67 ESR1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1199556-B1 Optical sensor for measuring an analyte and method of manufacturing the same METTLER TOLEDO GMBH (CH) 2004-05-06 EP claimed
US-6653148-B2 Optical sensor for determining an analyte, and method of manufacturing the optical sensor METTLER-TOLEDO GMBH (CH) 2003-11-25 US claimed
US-20030017078-A1 Sensor matrix that is made up substantially of a fluoropolymer containing luminescent indicator with a metal complex of ruthenium, rhenium, rhodium or iridium, and with at least one at least partially fluorinated ligand. METTLER-TOLEDO GMBH (CH) 2003-01-23 US claimed
EP-1199556-A1 Optical sensor for measuring an analyte and method of manufacturing the same Mettler-Toledo GmbH (CH) 2002-04-24 EP claimed
US-20060171845-A1 Sensors for measuring analytes DAKOTA TECHNOLOGIES, INC. 2006-08-03 US disclosed
EP-1199556-B1 Optical sensor for measuring an analyte and method of manufacturing the same METTLER TOLEDO GMBH (CH) 2004-05-06 EP disclosed
US-6653148-B2 Optical sensor for determining an analyte, and method of manufacturing the optical sensor METTLER-TOLEDO GMBH (CH) 2003-11-25 US disclosed
US-20030017078-A1 Sensor matrix that is made up substantially of a fluoropolymer containing luminescent indicator with a metal complex of ruthenium, rhenium, rhodium or iridium, and with at least one at least partially fluorinated ligand. METTLER-TOLEDO GMBH (CH) 2003-01-23 US disclosed
EP-1199556-A1 Optical sensor for measuring an analyte and method of manufacturing the same Mettler-Toledo GmbH (CH) 2002-04-24 EP disclosed