Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25509448 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL5951898 | 0.78 | HPGD (0.40) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL5951630 | 0.78 | KDM4E (0.39) | ALDH1A1CYP2A6MAPTHSD17B10TSHR | |
| SCHEMBL22095384 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTHSD17B10TSHRTDP1 | |
| SCHEMBL14983518 | 0.75 | TRPM4 (0.42) | ALDH1A1CYP2A6MAPTHSD17B10TSHR | |
| SCHEMBL8624869 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1CYP1A2HPGD | |
| SCHEMBL5952980 | 0.75 | KCNA3 (0.41) | ALDH1A1CYP2A6MAPTHSD17B10TSHR | |
| SCHEMBL14983442 | 0.75 | HTR1B (0.41) | ALDH1A1CYP2A6 | |
| SCHEMBL24012376 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL29555556 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668643-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | Braskem America, Inc. (US) | 2020-06-24 | — | — | EP | claimed |
| WO-2019036376-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. (US) | 2019-02-21 | — | — | WO | claimed |
| US-20190046965-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. | 2019-02-14 | — | — | US | claimed |
| US-11291981-B2 | Boron-based electron donors for Ziegler-Natta catalyst systems | BRASKEM AMERICA, INC. (US) | 2022-04-05 | — | — | US | disclosed |
| US-11291981-B2 | Boron-based electron donors for Ziegler-Natta catalyst systems | BRASKEM AMERICA, INC. (US) | 2022-04-05 | — | — | US | disclosed |
| EP-3668643-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | Braskem America, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036376-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019036376-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
| US-20190046965-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. | 2019-02-14 | — | — | US | disclosed |
| US-20190046965-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. | 2019-02-14 | — | — | US | disclosed |
| US-9056822-B2 | Method for producing polycyclic aromatic compound substituted by aryl group | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20130137271-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137271-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | ALDH1A1 317/4885CYP2A6 64/4885MAPT 3693/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | ALDH1A1 198/4885CYP2A6 78/4885MAPT 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.